GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
FGD4 |
FullNmae |
FYVE, RhoGEF and PH domain containing 4 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:19125 |
EnsembleID |
ENSG00000139132 |
Uniprot |
Q96M96 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
FGD4 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
FGD4 |
GO:0001726,GO:0003779,GO:0005085,GO:0005085,GO:0005737,GO:0005737,GO:0005794,GO:0005829,GO:0005856,GO:0007010,GO:0007010,GO:0008360,GO:0030027,GO:0030036,GO:0030175,GO:0031267,GO:0043087,GO:0046847,GO:0046847,GO:0046872,GO:0051056 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
AR |
FGD4 |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
GATA2 |
FGD4 |
18971253
19941826
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
YBX1 |
FGD4 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
FOXP3 |
FGD4 |
20554955
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
PRDM14 |
FGD4 |
18971253
20953172
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
FGD4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
FGD4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
FGD4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F1 |
FGD4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
FGD4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
FGD4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
FGD4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
MITF |
FGD4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TRIM28 |
FGD4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TAL1 |
FGD4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS000075AB0E |
FGD4 |
22100165
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000086A4D |
FGD4 |
22100165
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001A6D0C |
FGD4 |
22100165
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000029D9F1 |
FGD4 |
22100165
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000034B6F5 |
FGD4 |
22100165
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000079F78 |
FGD4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002E1509 |
FGD4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00004AC389 |
FGD4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000C7662 |
FGD4 |
23313552
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000034979B |
FGD4 |
23313552
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000039D790 |
FGD4 |
23313552
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000237AF9 |
FGD4 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000F4AC3 |
FGD4 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000C48FA |
FGD4 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000003FD55 |
FGD4 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001496AE |
FGD4 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000075AAA0 |
FGD4 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
PRKCA |
FGD4 |
25348397
|
N/A |
physical interaction |
ComPPI |
ACTA1 |
FGD4 |
11429692
14525934
25348397
27898060
9668039
|
N/A |
experimental interaction detection,in vitro |
ComPPI,HPRD,OmniPath |
FGD4 |
CAPZA2 |
25348397
|
N/A |
physical interaction |
ComPPI |
ZNF653 |
FGD4 |
30033366
30476227
|
additive genetic interaction defined by inequality |
genetic interference |
TheBiogrid |
Visualization