Gene Information gene info

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GENE：GGPS1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GGPS1
FullNmae geranylgeranyl diphosphate synthase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4249
EnsembleID ENSG00000152904
Uniprot O95749

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GGPS1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GGPS1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GGPS1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
GGPS1 GO:0004161,GO:0004311,GO:0004311,GO:0004337,GO:0004659,GO:0005515,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0006720,GO:0008299,GO:0030018,GO:0033384,GO:0033386,GO:0042802,GO:0045337,GO:0046872,GO:0048471

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GGPS1 hsa:9453 path:hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human)
GGPS1 hsa:9453 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 GGPS1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
ATOX1 GGPS1 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 GGPS1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 GGPS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GGPS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GGPS1 18971253 21983072 trascriptional regulation,stimulation inferred by curator TFlink
FOS GGPS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GGPS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 GGPS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004E008F GGPS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 GGPS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 GGPS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007F792 GGPS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED GGPS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 GGPS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA GGPS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF GGPS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000038446A GGPS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 GGPS1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GGPS1 FDPS 25361965 interaction type N/A PTMCode2
FDPS GGPS1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FOXD4L6 GGPS1 25348397 N/A physical interaction ComPPI
IQGAP1 GGPS1 25348397 N/A physical interaction ComPPI
SDCBP GGPS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ADCYAP1 GGPS1 25348397 N/A physical interaction ComPPI
ATOX1 GGPS1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRIM25 GGPS1 25348397 N/A physical interaction ComPPI
TRAF3IP3 GGPS1 25348397 N/A physical interaction ComPPI
IKZF5 GGPS1 25348397 N/A physical interaction ComPPI
SNRPE GGPS1 25348397 N/A physical interaction ComPPI
HOXA5 GGPS1 25348397 N/A physical interaction ComPPI
RPS14 GGPS1 25348397 N/A physical interaction ComPPI
TRIM41 GGPS1 25348397 N/A physical interaction ComPPI
RPS4X GGPS1 25348397 N/A physical interaction ComPPI
TADA2B GGPS1 25348397 N/A physical interaction ComPPI
UNKL GGPS1 25348397 N/A physical interaction ComPPI
SLTM GGPS1 25348397 N/A physical interaction ComPPI
CCDC69 GGPS1 25348397 N/A physical interaction ComPPI
RNASE3 GGPS1 25348397 N/A physical interaction ComPPI
TUSC1 GGPS1 25348397 N/A physical interaction ComPPI
ZNF696 GGPS1 25348397 N/A physical interaction ComPPI
FAM120A GGPS1 25348397 N/A physical interaction ComPPI
UNK GGPS1 25348397 N/A physical interaction ComPPI
TULP3 GGPS1 25348397 N/A physical interaction ComPPI
SPATA24 GGPS1 25348397 N/A physical interaction ComPPI
CCDC85C GGPS1 25348397 N/A physical interaction ComPPI
GGPS1 ODAPH 25348397 N/A physical interaction ComPPI
GGPS1 TAFA3 25348397 N/A physical interaction ComPPI
GGPS1 FOXD4 25348397 N/A physical interaction ComPPI
GGPS1 ZNF669 25348397 N/A physical interaction ComPPI
GGPS1 ZBTB42 25348397 N/A physical interaction ComPPI
GGPS1 ZNF517 25348397 N/A physical interaction ComPPI
GGPS1 GGPS1 24234451 25416956 physical association two hybrid array,two hybrid prey pooling approach IntAct
GGPS1 SRM 26224411 27898060 N/A N/A OmniPath

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