Gene Information gene info

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GENE：NPL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NPL
FullNmae N-acetylneuraminate pyruvate lyase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16781
EnsembleID ENSG00000135838
Uniprot Q9BXD5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NPL immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NPL GO:0005515,GO:0005829,GO:0005975,GO:0008747,GO:0008747,GO:0008747,GO:0019262,GO:0019262,GO:0019262,GO:0019262,GO:0042802

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NPL hsa:80896 path:hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human)
NPL hsa:80896 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 NPL 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 NPL 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NPL 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 NPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 NPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
PEG10 NPL 25348397 N/A physical interaction ComPPI
NTAQ1 NPL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
APP NPL 25348397 N/A physical interaction ComPPI

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