GENE：STK38
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | STK38 |
| FullNmae | serine/threonine kinase 38 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17847 |
| EnsembleID | ENSG00000112079 |
| Uniprot | Q15208 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| STK38 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| STK38 | GO:0000287,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0005829,GO:0006468,GO:0018105,GO:0031435,GO:0035556,GO:0035556,GO:0036211,GO:0043407,GO:0045296,GO:0098978,GO:0099173,GO:0106310 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | STK38 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | STK38 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | STK38 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | STK38 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | STK38 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | STK38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | STK38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | STK38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | STK38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | STK38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | STK38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | STK38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000031602A | STK38 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000324096 | STK38 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000BD6DC | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000009EA8F | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F6E49 | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000ECE9C | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004E02F2 | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000004BACE | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000001A7A | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000008F0CF | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D2680 | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | STK38 | 20371350 21572407 22012620 23592263 24398324 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000239117 | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D0874 | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000083D87 | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C48FA | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000080D0A | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000058276F | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | STK38 | 22473208 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A8BC6 | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000137EDE | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019907A | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000035AC91 | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00006097A6 | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002367FA | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002ECEE4 | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F4657 | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040828B | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000024DFCE | STK38 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| STK38 | YAP1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| STK38 | STK38 | 22135298 | phosphorylation | N/A | PhosphoSite |
| STK38 | RAB3IP | 22135298 | phosphorylation | N/A | PhosphoSite |
| STK38 | KIF23 | 22135298 | phosphorylation | N/A | PhosphoSite |
| PRKACA | STK38 | 22135298 | phosphorylation | N/A | PhosphoSite |
| GSK3B | STK38 | 22135298 | phosphorylation | N/A | PhosphoSite |
| STK4 | STK38 | 22135298 | phosphorylation | N/A | PhosphoSite |
| STK38 | S100B | 25361965 | interaction type | N/A | PTMCode2 |
| S100B | STK38 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| S100B | STK38 | 14525934 14661952 25348397 9774336 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| ISG15 | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| NPM1 | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| CALM1 | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| KRT31 | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| HSP90AB1 | STK38 | 22939624 24234451 25348397 | physical association | anti tag coimmunoprecipitation,luminescence based mammalian interactome mapping | ComPPI,IntAct |
| EHMT2 | STK38 | 24234451 25348397 26028330 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| NOTCH1 | STK38 | 23022380 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| GTF2F2 | STK38 | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
| HERC5 | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| PRPH | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| YWHAB | STK38 | 14525934 15324660 24234451 25348397 | physical association | coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,IntAct |
| YWHAZ | STK38 | 14525934 15324660 24234451 25348397 | physical association | coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,IntAct |
| HSP90AA1 | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| SOCS2 | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| TRAF3 | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| HEY1 | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | MOB2 | 14525934 15067004 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| STK38 | CTDP1 | 14525934 15670829 24234451 25348397 | physical association | affinity chromatography technology,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,IntAct |
| STK38 | MOB1A | 15197186 24234451 25348397 25852190 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STK38 | TRIM25 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | MYSM1 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | AGO3 | 19167051 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STK38 | VHL | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | ARRB1 | 17620599 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STK38 | ARRB2 | 17620599 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STK38 | TCF3 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | MOB1B | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | MAP3K1 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | MAP3K2 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | GRK5 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | MTOR | 19875983 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STK38 | RICTOR | 19875983 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STK38 | MAPKAP1 | 19875983 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STK38 | MAGOH | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | SMURF1 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | HSP90AA2P | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | PAN2 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | FBXO6 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | ZBTB1 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | LUZP4 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | CDC37 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | PRSS1 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | MPP1 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | EWSR1 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | H2AC20 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | H2BC21 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | ID2 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | GAN | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | CDK8 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | CDK19 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | SKI | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | RC3H1 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | CCNB1 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | CRBN | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | MARVELD2 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | SLC25A25 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | CYLD | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | GATA3 | 24234451 25348397 26028330 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| H3C1 | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| EIF4A3 | STK38 | 25348397 | N/A | physical interaction | ComPPI |
| STK38 | STK38 | 12493777 14525934 | N/A | experimental interaction detection | HPRD |
| PRKACA | STK38 | 22142472 27898060 | N/A | N/A | OmniPath |
| STK38 | YAP1 | 18640976 24462114 24658687 25180175 25601544 25751140 27898060 | N/A | N/A | OmniPath |
| STK11 | STK38 | 12840024 27898060 | N/A | N/A | OmniPath |
| STK38 | MAP3K1 | 17906693 27898060 | inhibition | N/A | OmniPath |
| STK38 | MAP3K2 | 17906693 27898060 | inhibition | N/A | OmniPath |
| STK24 | STK38 | 12493777 16314523 27898060 | stimulant | N/A | OmniPath |
| STK38 | RAB3IP | 23435566 27898060 | N/A | N/A | OmniPath |