Gene Information gene info

GENE:AMOTL1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AMOTL1
FullNmae angiomotin like 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17811
EnsembleID ENSG00000166025
Uniprot Q8IY63

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AMOTL1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AMOTL1 GO:0001525,GO:0003365,GO:0005515,GO:0005829,GO:0005886,GO:0005923,GO:0005923,GO:0016055,GO:0030036,GO:0030334,GO:0031410,GO:0035329,GO:0042802

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AMOTL1 hsa:154810 path:hsa04530 Tight junction - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR AMOTL1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 AMOTL1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 AMOTL1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 AMOTL1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 AMOTL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AMOTL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 AMOTL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AMOTL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 AMOTL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS AMOTL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF AMOTL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 AMOTL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 AMOTL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 AMOTL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE AMOTL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000183BED AMOTL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171CD1 AMOTL1 20371350 21572407 22012620 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C AMOTL1 20371350 21572407 22012620 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001925C1 AMOTL1 20371350 21572407 22012620 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D AMOTL1 20371350 21572407 22012620 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 AMOTL1 20371350 21572407 22012620 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A AMOTL1 20371350 21572407 22012620 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 AMOTL1 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 AMOTL1 20371350 21572407 22012620 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E AMOTL1 20371350 21572407 22012620 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D AMOTL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE AMOTL1 20371350 21572407 22012620 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 AMOTL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D AMOTL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 AMOTL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000555DA6 AMOTL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 AMOTL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000224AEA AMOTL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 AMOTL1 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000017EE98 AMOTL1 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 AMOTL1 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDCD1 AMOTL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF AMOTL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000003FD55 AMOTL1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001CF056 AMOTL1 23824327 25416803 26701625 27418678 mrna cleavage,inhibition clip TarBase
URS00003003B4 AMOTL1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000D6C3F AMOTL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 AMOTL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000004BACE AMOTL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001012BC AMOTL1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FHL3 AMOTL1 25348397 N/A physical interaction ComPPI
AMOT AMOTL1 19615732 24234451 24255178 24366813 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NF2 AMOTL1 21481793 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS5 AMOTL1 18850735 24234451 25348397 association tandem affinity purification ComPPI,IntAct
WWP2 AMOTL1 25348397 N/A physical interaction ComPPI
WWC1 AMOTL1 25348397 N/A physical interaction ComPPI
NEDD4L AMOTL1 25348397 N/A physical interaction ComPPI
ALOX5 AMOTL1 25348397 N/A physical interaction ComPPI
YAP1 AMOTL1 24234451 24255178 24366813 25348397 25751139 colocalization,association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
TLK2 AMOTL1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
WWOX AMOTL1 25348397 N/A physical interaction ComPPI
NEDD4 AMOTL1 25348397 N/A physical interaction ComPPI
MAGI2 AMOTL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
WWTR1 AMOTL1 20972459 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LATS1 AMOTL1 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HECW2 AMOTL1 25348397 N/A physical interaction ComPPI
SHMT2 AMOTL1 25348397 N/A physical interaction ComPPI
SUZ12 AMOTL1 25348397 N/A physical interaction ComPPI
LATS2 AMOTL1 25348397 N/A physical interaction ComPPI
NXF1 AMOTL1 25348397 N/A physical interaction ComPPI
USP9X AMOTL1 25348397 N/A physical interaction ComPPI
CAPZA2 AMOTL1 25348397 N/A physical interaction ComPPI
MOV10 AMOTL1 25348397 N/A physical interaction ComPPI
AMOTL1 COBLL1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
AMOTL1 HMBOX1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
IKBKG AMOTL1 24234451 30561431 association virotrap IntAct
TANK AMOTL1 24234451 30561431 association virotrap IntAct
TNIP2 AMOTL1 24234451 30561431 association virotrap IntAct

Visualization