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GENE：CD84

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CD84
FullNmae CD84 molecule
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1704
EnsembleID ENSG00000066294
Uniprot Q9UIB8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CD84 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CD84 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
CD84 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
CD84 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CD84 GO:0002250,GO:0005515,GO:0005886,GO:0005886,GO:0006914,GO:0006952,GO:0007156,GO:0009897,GO:0032685,GO:0032701,GO:0032715,GO:0032760,GO:0033004,GO:0042110,GO:0042802,GO:0043030,GO:0043231,GO:0043305,GO:0045087,GO:0071639,GO:2001256

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SH2D1A CD84 12163025 19150402 23180781 physical association two hybrid,peptide array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CD84 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 CD84 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CD84 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CD84 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CD84 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CD84 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 CD84 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CD84 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 CD84 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CD84 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CD84 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000486E0B CD84 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D CD84 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 CD84 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 CD84 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075D860 CD84 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 CD84 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 CD84 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 CD84 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 CD84 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 CD84 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA CD84 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB CD84 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CD84 SH2D1A 25361965 interaction type N/A PTMCode2
SH2D1A CD84 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PTPN11 CD84 25348397 N/A physical interaction ComPPI
CUL3 CD84 25348397 N/A physical interaction ComPPI
SH2D1A CD84 11477068 12225753 12928397 14525934 24234451 25348397 association two hybrid,coimmunoprecipitation,experimental interaction detection,nuclear magnetic resonance,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
CD84 SH2D1B 11689425 12115647 12928397 14525934 23322602 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
CD84 ABL2 23322602 24234451 25348397 association pull down ComPPI,IntAct
CD84 CD84 11238035 11389028 11414741 11564780 12621057 14525934 17563375 24234451 N/A cosedimentation in solution,experimental interaction detection,molecular sieving,x-ray crystallography,two hybrid HPRD,IntAct

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