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GENE：COL6A1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol COL6A1
FullNmae collagen type VI alpha 1 chain
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2211
EnsembleID ENSG00000142156
Uniprot P12109

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
COL6A1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
COL6A1 GO:0001649,GO:0005518,GO:0005576,GO:0005576,GO:0005576,GO:0005589,GO:0005765,GO:0005788,GO:0007155,GO:0016020,GO:0030020,GO:0030020,GO:0032991,GO:0035987,GO:0042383,GO:0048407,GO:0062023,GO:0062023,GO:0062023,GO:0070062,GO:0071230

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
COL6A1 hsa:1291 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
COL6A1 hsa:1291 path:hsa04510 Focal adhesion - Homo sapiens (human)
COL6A1 hsa:1291 path:hsa04512 ECM-receptor interaction - Homo sapiens (human)
COL6A1 hsa:1291 path:hsa04974 Protein digestion and absorption - Homo sapiens (human)
COL6A1 hsa:1291 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 COL6A1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 COL6A1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 COL6A1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 COL6A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF COL6A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 COL6A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 COL6A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS COL6A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 COL6A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SMAD3 COL6A1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 COL6A1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000FC8EB COL6A1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000070B1D COL6A1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 COL6A1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D COL6A1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 COL6A1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
DCN COL6A1 25361965 interaction type N/A PTMCode2
COL6A1 DCN 25361965 interaction type N/A PTMCode2
LAMB1 COL6A1 25361965 interaction type N/A PTMCode2
COL6A1 LAMB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PDIA3 COL6A1 25348397 N/A physical interaction ComPPI
PDGFB COL6A1 25348397 N/A physical interaction ComPPI
PDGFA COL6A1 25348397 N/A physical interaction ComPPI
VHL COL6A1 25348397 N/A physical interaction ComPPI
LAMB1 COL6A1 10407855 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
DNAJB11 COL6A1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
COL2A1 COL6A1 14525934 1544908 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
OS9 COL6A1 25348397 N/A physical interaction ComPPI
TRIM25 COL6A1 25348397 N/A physical interaction ComPPI
WNT4 COL6A1 25348397 N/A physical interaction ComPPI
PLA2G10 COL6A1 25348397 N/A physical interaction ComPPI
MMP2 COL6A1 25348397 N/A physical interaction ComPPI
MMP9 COL6A1 25348397 N/A physical interaction ComPPI
FGF7 COL6A1 11973338 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
DEFA1 COL6A1 25348397 N/A physical interaction ComPPI
COL6A1 LGALS3BP 14525934 25348397 9501082 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
COL6A1 COL5A1 20979576 24234451 25348397 physical association two hybrid ComPPI,IntAct
COL6A1 DCN 25348397 N/A physical interaction ComPPI
COL6A1 MAG 25348397 N/A physical interaction ComPPI
COL6A1 FBXO6 25348397 N/A physical interaction ComPPI
COL6A1 RTBDN 25348397 N/A physical interaction ComPPI
COL6A1 COLEC11 25348397 N/A physical interaction ComPPI
COL6A1 COL9A1 25348397 N/A physical interaction ComPPI
COL6A1 C1QTNF9 25348397 N/A physical interaction ComPPI
COL6A1 PTPRK 25348397 N/A physical interaction ComPPI
COL6A1 PLOD1 25348397 N/A physical interaction ComPPI
COL6A1 LYZL1 25348397 N/A physical interaction ComPPI
COL6A1 LYPD1 25348397 N/A physical interaction ComPPI
COL6A1 WNT7A 25348397 N/A physical interaction ComPPI
COL6A1 INSL5 25348397 N/A physical interaction ComPPI
COL6A1 KLF17 24234451 30021884 physical association cross-linking study IntAct
HSD17B4 COL6A1 24234451 30021884 physical association cross-linking study IntAct

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