Gene Information gene info

  1. Home

GENE：DUSP10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DUSP10
FullNmae dual specificity phosphatase 10
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3065
EnsembleID ENSG00000143507
Uniprot Q9Y6W6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DUSP10 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DUSP10 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DUSP10 GO:0002819,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0008330,GO:0008330,GO:0008432,GO:0010633,GO:0016311,GO:0016791,GO:0017017,GO:0017018,GO:0030336,GO:0032496,GO:0033549,GO:0033549,GO:0033550,GO:0035970,GO:0043508,GO:0043508,GO:0045591,GO:0046329,GO:0048273,GO:0048709,GO:0048715,GO:0050680,GO:0051403,GO:0060266,GO:0070373,GO:0090335,GO:1903753,GO:1903753,GO:1905042,GO:1990264

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DUSP10 hsa:11221 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MAPK8 DUSP10 16166642 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
MAPK10 DUSP10 11359773 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAPK9 DUSP10 11359773 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAPK14 DUSP10 11157753 11359773 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAPK11 DUSP10 11359773 23180781 physical association anti tag coimmunoprecipitation InnateDB
PRDM1 DUSP10 20421211 23180781 physical association anti tag coimmunoprecipitation InnateDB
DUSP10 MAPK8 10391943 10597297 11283254 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR DUSP10 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 DUSP10 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 DUSP10 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 DUSP10 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 DUSP10 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 DUSP10 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 DUSP10 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 DUSP10 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 DUSP10 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 DUSP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DUSP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DUSP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 DUSP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DUSP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DUSP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 DUSP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DUSP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 DUSP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 DUSP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ATF2 DUSP10 17681939 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D DUSP10 22387553 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000009262D DUSP10 22387553 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000122ED0 DUSP10 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000000EF0B DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000002CF68 DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000FFE5F DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018CD09 DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F0130 DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000224AEA DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 DUSP10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 DUSP10 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 DUSP10 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MTOR DUSP10 22135298 phosphorylation N/A PhosphoSite
MAPK11 DUSP10 25361965 interaction type N/A PTMCode2
DUSP10 MAPK11 25361965 interaction type N/A PTMCode2
MAPK10 DUSP10 25361965 interaction type N/A PTMCode2
DUSP10 MAPK10 25361965 interaction type N/A PTMCode2
MAPK8 DUSP10 25361965 interaction type N/A PTMCode2
DUSP10 MAPK8 25361965 interaction type N/A PTMCode2
MAPK14 DUSP10 25361965 interaction type N/A PTMCode2
DUSP10 MAPK14 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAPK9 DUSP10 16288922 24234451 25348397 dephosphorylation reaction,physical association physical interaction,two hybrid array,phosphatase assay,two hybrid prey pooling approach ComPPI,IntAct
HOXA1 DUSP10 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ROR2 DUSP10 25348397 N/A physical interaction ComPPI
KRTAP3-2 DUSP10 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTB DUSP10 25348397 N/A physical interaction ComPPI
ERBB4 DUSP10 25348397 N/A physical interaction ComPPI
MAPK8 DUSP10 10391943 10597297 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
MAPK3 DUSP10 10597297 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
FHL2 DUSP10 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAPK14 DUSP10 10391943 10597297 11359773 14525934 20936779 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,two hybrid ComPPI,HPRD,IntAct
PTPN2 DUSP10 25348397 N/A physical interaction ComPPI
SNX2 DUSP10 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CASK DUSP10 25348397 N/A physical interaction ComPPI
MAPK10 DUSP10 11359773 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HTT DUSP10 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
DUSP10 MAPK11 25348397 N/A in vitro ComPPI
DUSP10 CMTM6 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DUSP10 FN1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DUSP10 RPS11 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DUSP10 SLX1A 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DUSP10 OTUD4 25348397 N/A physical interaction ComPPI
DUSP10 ACTBL2 25348397 N/A physical interaction ComPPI
DUSP10 ACTA2 25348397 N/A physical interaction ComPPI
DUSP10 EFHD1 25348397 N/A physical interaction ComPPI
DUSP10 PTK7 25348397 N/A physical interaction ComPPI
IGF1R DUSP10 25348397 N/A physical interaction ComPPI
MAPK10 DUSP10 11359773 27898060 N/A N/A OmniPath
DUSP10 MAPK10 11359773 27898060 inhibition N/A OmniPath
MAPK9 DUSP10 11359773 16288922 27898060 N/A N/A OmniPath
DUSP10 MAPK9 10597297 11359773 16288922 27898060 inhibition N/A OmniPath
MAPK14 DUSP10 10391943 10597297 11157753 11359773 20936779 27898060 N/A N/A OmniPath
DUSP10 MAPK14 10391943 10597297 11157753 11359773 11790549 20936779 27898060 inhibition N/A OmniPath
MTOR DUSP10 25568665 27898060 N/A N/A OmniPath
MAPK11 DUSP10 11359773 27898060 N/A N/A OmniPath
MAPK8 DUSP10 10391943 10597297 11283254 16166642 27898060 N/A N/A OmniPath
DUSP10 MAPK8 10391943 10597297 11283254 11790549 16166642 27898060 inhibition,stimulant N/A OmniPath

Visualization










  Return