Gene Information gene info

  1. Home

GENE：DUSP16

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DUSP16
FullNmae dual specificity phosphatase 16
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17909
EnsembleID ENSG00000111266
Uniprot Q9BY84

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DUSP16 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DUSP16 GO:0004721,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0006470,GO:0008330,GO:0008432,GO:0016311,GO:0016791,GO:0017017,GO:0017018,GO:0031410,GO:0033550,GO:0043409,GO:0043409,GO:0043508,GO:0045204,GO:0048273,GO:0051019

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DUSP16 hsa:80824 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
DUSP16 hsa:80824 path:hsa04148 Efferocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DUSP16 MAPK8IP1 12524447 23180781 23331499 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
ARRB2 DUSP16 15888437 23180781 physical association pull down InnateDB
DUSP16 MAPK8 11359773 11489891 23180781 physical association anti tag coimmunoprecipitation InnateDB
DUSP16 MAPK14 11359773 11489891 12794087 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAPK1 DUSP16 11359773 11489891 23180781 physical association anti tag coimmunoprecipitation InnateDB
DUSP16 MAPK9 11359773 14699111 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
MAPK14 DUSP16 23926106 dephosphorylation reaction,inhibition N/A SignaLink
DUSP16 MAPK8IP2 12524447 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
MAPK8IP1 DUSP16 20005715 interaction type N/A PSP,SignaLink
MAPK8IP2 DUSP16 12524447 18988627 20005715 interaction type N/A PSP,SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 DUSP16 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DUSP16 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 DUSP16 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 DUSP16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DUSP16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DUSP16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 DUSP16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DUSP16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DUSP16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DUSP16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DUSP16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DUSP16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 DUSP16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 DUSP16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 DUSP16 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 DUSP16 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 DUSP16 19074876 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
MAPK1 DUSP16 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
DUSP16 MAPK1 25361965 interaction type N/A PTMCode2
DUSP16 MAPK14 25361965 interaction type N/A PTMCode2
MAPK14 DUSP16 25361965 interaction type N/A PTMCode2
DUSP16 MAPK8IP1 25361965 interaction type N/A PTMCode2
MAPK8IP1 DUSP16 25361965 interaction type N/A PTMCode2
DUSP16 MAPK11 25361965 interaction type N/A PTMCode2
MAPK11 DUSP16 25361965 interaction type N/A PTMCode2
DUSP16 MAPK10 25361965 interaction type N/A PTMCode2
MAPK10 DUSP16 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAPK9 DUSP16 11359773 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
YWHAG DUSP16 24234451 25348397 28330616 association pull down ComPPI,IntAct
VBP1 DUSP16 25348397 N/A physical interaction ComPPI
MAPK1 DUSP16 11489891 12794087 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ERBB4 DUSP16 25348397 N/A physical interaction ComPPI
MAPK8 DUSP16 11489891 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MAPK14 DUSP16 11359773 11489891 14525934 14586399 20936779 24234451 25348397 physical association experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo ComPPI,HPRD,IntAct
YWHAB DUSP16 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
AIP DUSP16 25348397 N/A physical interaction ComPPI
IRS4 DUSP16 24234451 25348397 28330616 association pull down ComPPI,IntAct
PFKL DUSP16 24234451 25348397 28330616 association pull down ComPPI,IntAct
HAX1 DUSP16 24234451 25348397 28330616 association pull down ComPPI,IntAct
PTGES3 DUSP16 25348397 N/A physical interaction ComPPI
NXF2 DUSP16 25348397 N/A physical interaction ComPPI
CAD DUSP16 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 MAPK10 11359773 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
DUSP16 MAPK11 25348397 N/A in vitro ComPPI
DUSP16 MAPK8IP1 12524447 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DUSP16 MAPK8IP2 12524447 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
DUSP16 MLF1 25348397 N/A physical interaction ComPPI
DUSP16 KCTD20 25348397 N/A physical interaction ComPPI
DUSP16 HSPB1 25348397 N/A physical interaction ComPPI
DUSP16 HIGD1A 25348397 N/A physical interaction ComPPI
DUSP16 ARF5 25348397 N/A physical interaction ComPPI
DUSP16 DNAJB1 25348397 N/A physical interaction ComPPI
DUSP16 DUSP8 25348397 N/A physical interaction ComPPI
DUSP16 PRPF8 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 EIF3A 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 PSMC2 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 DNAJA2 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 LAS1L 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 TUBB2B 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 TUBB6 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 RCN2 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 BAG5 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 TUBA1C 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 AKAP8L 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 SNRNP200 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 NTPCR 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 DYNC1H1 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 MAP1B 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 GLUD1 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 DNAJB6 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 SEC16A 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 TUBAL3 24234451 25348397 28330616 association pull down ComPPI,IntAct
DUSP16 GABARAP 24234451 30021884 physical association cross-linking study IntAct
DUSP16 ARRB2 15888437 27898060 N/A N/A OmniPath
DUSP16 MAPK10 11359773 15888437 27898060 inhibition N/A OmniPath
MAPK9 DUSP16 11359773 14699111 27898060 N/A N/A OmniPath
DUSP16 MAPK9 11359773 11564882 14699111 27898060 inhibition N/A OmniPath
MAPK14 DUSP16 11359773 11489891 12794087 14586399 20936779 26186194 27898060 N/A N/A OmniPath
DUSP16 MAPK14 11359773 11489891 12794087 14586399 20936779 26186194 27898060 inhibition N/A OmniPath
MAPK1 DUSP16 11359773 11489891 12794087 15689616 27898060 stimulant N/A OmniPath
DUSP16 MAPK1 11359773 11489891 12794087 27898060 inhibition N/A OmniPath
DUSP16 MAPK8IP1 12524447 27898060 stimulant N/A OmniPath
MAPK8IP1 DUSP16 12524447 27898060 N/A N/A OmniPath
DUSP16 MAPK8 11359773 11489891 27898060 inhibition N/A OmniPath
DUSP16 MAPK8IP2 12524447 27898060 stimulant N/A OmniPath

Visualization










  Return