GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
FRG1 |
FullNmae |
FSHD region gene 1 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:3954 |
EnsembleID |
ENSG00000109536 |
Uniprot |
Q14331 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
FRG1 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
FRG1 |
GO:0000398,GO:0003723,GO:0005515,GO:0005730,GO:0006364,GO:0007517,GO:0015030,GO:0030018,GO:0051015,GO:0055120,GO:0071013,GO:0071013 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
E2F4 |
FRG1 |
17531812
18971253
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array,inferred by curator |
TFlink |
ETS1 |
FRG1 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
FRG1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
FRG1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
FRG1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXP1 |
FRG1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
FRG1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
MITF |
FRG1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TRIM28 |
FRG1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TAL1 |
FRG1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
ZNF263 |
FRG1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS0000065D58 |
FRG1 |
18668040
25416803
|
mrna cleavage,inhibition |
experimental interaction detection,experimental interaction detection,experimental interaction detection |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
RBPMS |
FRG1 |
21516116
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
LZTS2 |
FRG1 |
24234451
25348397
25416956
|
physical association |
two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid |
ComPPI,IntAct |
H2BC4 |
FRG1 |
25348397
|
N/A |
physical interaction |
ComPPI |
KRT40 |
FRG1 |
24234451
25348397
25416956
|
physical association |
two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid |
ComPPI,IntAct |
FRG1 |
SART3 |
19615732
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
FRG1 |
CAND1 |
25348397
|
N/A |
physical interaction |
ComPPI |
FRG1 |
HECW2 |
25348397
|
N/A |
physical interaction |
ComPPI |
FRG1 |
UBE2O |
25348397
|
N/A |
physical interaction |
ComPPI |
FRG1 |
H2BC11 |
25348397
|
N/A |
physical interaction |
ComPPI |
FRG1 |
HEY1 |
25348397
|
N/A |
physical interaction |
ComPPI |
FRG1 |
PTBP3 |
22575643
24234451
25348397
|
association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
FRG1 |
JUN |
24234451
25348397
25609649
|
association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
EXOSC8 |
FRG1 |
24234451
25348397
25416956
|
physical association |
two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid |
ComPPI,IntAct |
GNMT |
FRG1 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
H3C1 |
FRG1 |
24234451
25348397
29568061
|
association |
proximity-dependent biotin identification |
ComPPI,IntAct |
MKI67 |
FRG1 |
24234451
26949251
|
association |
anti tag coimmunoprecipitation |
IntAct |
Visualization