Gene Information gene info

GENE:GPS2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GPS2
FullNmae G protein pathway suppressor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4550
EnsembleID ENSG00000132522
Uniprot Q13227

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GPS2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GPS2 GO:0000122,GO:0003712,GO:0003713,GO:0003714,GO:0005095,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005667,GO:0005739,GO:0005829,GO:0006357,GO:0007254,GO:0010804,GO:0010875,GO:0017053,GO:0019216,GO:0030183,GO:0030332,GO:0034122,GO:0035360,GO:0045598,GO:0045599,GO:0045944,GO:0046329,GO:0050728,GO:0050859,GO:0098780,GO:1900045

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GPS2 hsa:2874 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GPS2 EMD 17620012 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAP3K7CL GPS2 16189514 23180781 physical association pull down InnateDB
ATF4 GPS2 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 GPS2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 GPS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GPS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
NR0B2 GPS2 25361965 interaction type N/A PTMCode2
GPS2 NR0B2 25361965 interaction type N/A PTMCode2
GPS2 TBL1X 25361965 interaction type N/A PTMCode2
TBL1X GPS2 25361965 interaction type N/A PTMCode2
HDAC3 GPS2 25361965 interaction type N/A PTMCode2
GPS2 HDAC3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RBPMS GPS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GOLGA2 GPS2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
VPS37C GPS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDC5L GPS2 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HOXA1 GPS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
OIP5 GPS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RALBP1 GPS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ATF4 GPS2 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
PPFIA1 GPS2 25348397 N/A physical interaction ComPPI
KRT31 GPS2 24234451 25348397 25416956 physical association physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP3-3 GPS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SETDB1 GPS2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MAPK3 GPS2 25348397 N/A physical interaction ComPPI
EP300 GPS2 10846067 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
HDAC3 GPS2 11931768 14525934 16980585 17895379 21258344 23752268 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
THRA GPS2 25348397 N/A physical interaction ComPPI
THRB GPS2 25348397 N/A physical interaction ComPPI
NCOR2 GPS2 25348397 N/A molecular sieving,nuclear magnetic resonance,pull down,physical interaction,physical interaction ComPPI
NCOR1 GPS2 11931768 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SIN3A GPS2 25348397 N/A physical interaction ComPPI
TRIP6 GPS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DBNL GPS2 25348397 N/A physical interaction ComPPI
DAPK3 GPS2 25348397 N/A physical interaction ComPPI
RMND5A GPS2 25348397 N/A physical interaction ComPPI
PPFIA3 GPS2 25348397 N/A physical interaction ComPPI
XPO1 GPS2 25348397 N/A physical interaction ComPPI
MSH4 GPS2 25348397 N/A physical interaction ComPPI
CCNA1 GPS2 14525934 15159402 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
NR0B2 GPS2 17895379 24234451 25348397 N/A pull down,physical interaction ComPPI,IntAct
AKAP8L GPS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ANKRD11 GPS2 25348397 N/A physical interaction ComPPI
HNF4A GPS2 25348397 N/A physical interaction ComPPI
GPS2 TBL1X 11931768 14525934 21240272 24943844 25348397 26070566 26186194 27898060 N/A experimental interaction detection,fluorescence polarization spectroscopy,pull down,physical interaction,in vitro ComPPI,HPRD,OmniPath
GPS2 MAP3K7CL 14525934 16189514 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid ComPPI,HPRD,IntAct
GPS2 BRME1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GPS2 PBK 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GPS2 SPDL1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GPS2 HDAC5 25348397 N/A physical interaction ComPPI
GPS2 CHD3 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GPS2 TP53 11486030 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
GPS2 CNOT2 16712523 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GPS2 HDAC1 17895379 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
GPS2 NR5A2 25348397 N/A physical interaction ComPPI
GPS2 NR1H4 25348397 N/A physical interaction ComPPI
GPS2 MSH5 25348397 N/A physical interaction ComPPI
GPS2 TFIP11 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GPS2 ARMC8 25348397 N/A physical interaction ComPPI
GPS2 MKLN1 25348397 N/A physical interaction ComPPI
GPS2 MAEA 25348397 N/A physical interaction ComPPI
GPS2 DCTN4 25348397 N/A physical interaction ComPPI
GPS2 RANBP10 25348397 N/A physical interaction ComPPI
GPS2 CYTH3 25348397 N/A physical interaction ComPPI
GPS2 GID4 25348397 N/A physical interaction ComPPI
GPS2 TRIM68 25348397 N/A physical interaction ComPPI
GPS2 GID8 25348397 N/A physical interaction ComPPI
GPS2 FOXK2 25348397 N/A physical interaction ComPPI
GPS2 AP5Z1 25348397 N/A physical interaction ComPPI
GPS2 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
GPS2 CREB1 25348397 N/A physical interaction ComPPI
GPS2 DCTN6 25348397 N/A physical interaction ComPPI
GPS2 DCTN3 25348397 N/A physical interaction ComPPI
GPS2 YPEL5 25348397 N/A physical interaction ComPPI
GPS2 PRMT6 25348397 N/A physical interaction ComPPI
GPS2 NINL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
GPS2 NANOGP8 25348397 N/A physical interaction ComPPI
GPS2 NANOG 25348397 N/A physical interaction ComPPI
GPS2 TBL1Y 25348397 N/A physical interaction ComPPI
GPS2 ACTR1B 25348397 N/A physical interaction ComPPI
GPS2 HNRNPH1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 INTS11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 NDOR1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 POU2AF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 KRT34 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 CYSRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 KRTAP13-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 KRTAP6-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 FHL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 KRT27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 BAG4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 ATF5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 DAZAP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TBL1XR1 GPS2 11931768 14525934 21258344 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
ACTR10 GPS2 25348397 N/A physical interaction ComPPI
UBTD2 GPS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SESTD1 GPS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP3-1 GPS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP11-1 GPS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 GPS2 11486030 14525934 N/A experimental interaction detection HPRD
ATF4 GPS2 16189514 25416956 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009AEA6F GPS2 27087310 direct interaction,inhibition N/A NPInter

Visualization