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GENE：HSD17B11

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HSD17B11
FullNmae hydroxysteroid 17-beta dehydrogenase 11
LocusType gene with protein product
Status Approved
HGNC_id HGNC:22960
EnsembleID ENSG00000198189
Uniprot Q8NBQ5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HSD17B11 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HSD17B11 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HSD17B11 GO:0004303,GO:0004303,GO:0005515,GO:0005737,GO:0005783,GO:0005811,GO:0005811,GO:0005829,GO:0006703,GO:0006710,GO:0016229,GO:0016229,GO:0016616

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HSD17B11 hsa:51170 path:hsa00140 Steroid hormone biosynthesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR HSD17B11 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 HSD17B11 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 HSD17B11 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 HSD17B11 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 HSD17B11 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 HSD17B11 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 HSD17B11 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 HSD17B11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HSD17B11 18971253 21549806 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HSD17B11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HSD17B11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HSD17B11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 HSD17B11 21549806 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 HSD17B11 21549806 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 HSD17B11 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
ADIPOQ HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN9 HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
JUN HSD17B11 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
VAPA HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PEX19 HSD17B11 25348397 N/A physical interaction ComPPI
UBC HSD17B11 25348397 N/A physical interaction ComPPI
NTRK1 HSD17B11 25348397 N/A physical interaction ComPPI
SERPINE1 HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RASGRP3 HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BRF2 HSD17B11 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EHHADH HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATXN3 HSD17B11 25348397 N/A physical interaction ComPPI
NEU1 HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLP2 HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ELAVL1 HSD17B11 25348397 N/A physical interaction ComPPI
STX5 HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SEC22B HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRAF2 HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FBXO6 HSD17B11 25348397 N/A physical interaction ComPPI
PTP4A3 HSD17B11 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IL13RA2 HSD17B11 25348397 N/A physical interaction ComPPI
TTPA HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
OTULINL HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSD17B11 AGPAT3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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