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GENE：KIF3A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KIF3A
FullNmae kinesin family member 3A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6319
EnsembleID ENSG00000131437
Uniprot Q9Y496

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KIF3A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KIF3A GO:0003777,GO:0005515,GO:0005524,GO:0005813,GO:0005814,GO:0005829,GO:0005871,GO:0005874,GO:0005876,GO:0005929,GO:0005929,GO:0006996,GO:0008017,GO:0008089,GO:0008574,GO:0010457,GO:0015031,GO:0015630,GO:0016887,GO:0016939,GO:0019903,GO:0030507,GO:0031267,GO:0034454,GO:0060271,GO:0060271,GO:0070062,GO:0072383,GO:0097542,GO:1902414,GO:1904115

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KIF3A hsa:11127 path:hsa04340 Hedgehog signaling pathway - Homo sapiens (human)
KIF3A hsa:11127 path:hsa04814 Motor proteins - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
KIF3A KIF3B 11208056 11226259 11449277 14603322 15618519 15852005 17641202 18497258 18820483 19081070 19565474 19718039 19853559 20215540 20375059 20643644 20956384 21602792 23031257 26192618 association N/A ACSN
SMO KIF3A 11208056 11226259 11449277 14603322 15618519 17641202 18497258 18820483 19081070 19565474 19853559 20215540 20375059 23031257 26192618 interaction type N/A ACSN
RAB23 KIF3A 11449277 18497258 20375059 26192618 interaction type N/A ACSN
KIF3A SUFU 11208056 14603322 20643644 20956384 26192618 interaction type N/A ACSN
KIF3A ULK3 11208056 14603322 20643644 20956384 26192618 interaction type N/A ACSN
KIF3A NEK1 14690447 23180781 physical association two hybrid InnateDB
DUSP26 KIF3A 19043453 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
APP KIF3A 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 KIF3A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 KIF3A 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 KIF3A 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 KIF3A 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000458AD2 KIF3A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C85C7 KIF3A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000057FDB8 KIF3A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 KIF3A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000239117 KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0874 KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 KIF3A 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000435A77 KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000038718E KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 KIF3A 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD KIF3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E KIF3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A KIF3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 KIF3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 KIF3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 KIF3A 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00005586D0 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004AF715 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000016FD1A KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000003ABC4 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003ACE11 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003FBC84 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000038446A KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C0099 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000006372A KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000021202F KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB14 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C1E1 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000355E82 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000425000 KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041FA2C KIF3A 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CAMK2A KIF3A 22135298 phosphorylation N/A PhosphoSite
AP3B1 KIF3A 25361965 interaction type N/A PTMCode2
KIF3A AP3B1 25361965 interaction type N/A PTMCode2
RPGR KIF3A 25361965 interaction type N/A PTMCode2
KIF3A RPGR 25361965 interaction type N/A PTMCode2
PPP1R15A KIF3A 25361965 interaction type N/A PTMCode2
KIF3A PPP1R15A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SSNA1 KIF3A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RAN KIF3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARL8A KIF3A 25348397 N/A physical interaction ComPPI
STN1 KIF3A 25348397 N/A physical interaction ComPPI
NOTCH1 KIF3A 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
GRB2 KIF3A 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
USP7 KIF3A 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LIG4 KIF3A 25348397 N/A physical interaction ComPPI
SLC9A3R2 KIF3A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NTRK1 KIF3A 25348397 N/A physical interaction ComPPI
CASP1 KIF3A 25348397 N/A physical interaction ComPPI
APTX KIF3A 25348397 N/A physical interaction ComPPI
KIFAP3 KIF3A 16298999 24234451 25348397 26496610 27173435 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
MAP3K10 KIF3A 14525934 25348397 9427749 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
RPA1 KIF3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCTN1 KIF3A 23386061 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
CFTR KIF3A 25348397 N/A physical interaction ComPPI
TRIM29 KIF3A 25348397 N/A physical interaction ComPPI
MAP3K11 KIF3A 14525934 25348397 9427749 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
KIF3B KIF3A 14525934 24234451 25348397 26496610 27173435 7559760 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,HPRD,IntAct
EXOC3 KIF3A 25348397 N/A physical interaction ComPPI
ARRB1 KIF3A 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARRB2 KIF3A 23877428 24234451 25348397 physical association bimolecular fluorescence complementation ComPPI,IntAct
DUSP14 KIF3A 25348397 N/A physical interaction ComPPI
VHL KIF3A 25348397 N/A physical interaction ComPPI
PLCD1 KIF3A 25348397 N/A physical interaction ComPPI
NEK1 KIF3A 14525934 14690447 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PKP1 KIF3A 25348397 N/A physical interaction ComPPI
SSX2 KIF3A 25348397 N/A physical interaction ComPPI
AP3B1 KIF3A 25348397 N/A two hybrid,pull down,physical interaction ComPPI
RANBP2 KIF3A 25348397 N/A physical interaction ComPPI
H3-3A KIF3A 25348397 N/A physical interaction ComPPI
PKP3 KIF3A 25348397 N/A physical interaction ComPPI
PREP KIF3A 25348397 N/A physical interaction ComPPI
GAK KIF3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DTNBP1 KIF3A 25348397 N/A physical interaction ComPPI
SSH2 KIF3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF3C KIF3A 14525934 24234451 25348397 26496610 27898060 9450952 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct,OmniPath
RAB11FIP5 KIF3A 24234451 24591568 25348397 physical association pull down ComPPI,IntAct
RGS20 KIF3A 25348397 N/A physical interaction ComPPI
PLEKHA5 KIF3A 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MED4 KIF3A 25348397 N/A physical interaction ComPPI
ACP3 KIF3A 25348397 N/A physical interaction ComPPI
TNFRSF8 KIF3A 25348397 N/A physical interaction ComPPI
FASN KIF3A 25348397 N/A physical interaction ComPPI
CTNNBL1 KIF3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIFBP KIF3A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SELENBP1 KIF3A 25348397 N/A physical interaction ComPPI
DNPEP KIF3A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CEP170 KIF3A 23386061 24234451 25348397 colocalization,physical association physical interaction,fluorescence microscopy,inference by socio-affinity scoring ComPPI,IntAct
LYPLA2 KIF3A 25348397 N/A physical interaction ComPPI
NUF2 KIF3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX34 KIF3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SCLT1 KIF3A 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PI4K2A KIF3A 25348397 N/A physical interaction ComPPI
APP KIF3A 25348397 N/A physical interaction ComPPI
DISC1 KIF3A 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
XRCC4 KIF3A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KIF3A TYW3 25348397 N/A physical interaction ComPPI
KIF3A HEPHL1 25348397 N/A physical interaction ComPPI
KIF3A ATG9B 25348397 N/A physical interaction ComPPI
KIF3A VSIG8 25348397 N/A physical interaction ComPPI
KIF3A MFHAS1 25348397 N/A physical interaction ComPPI
KIF3A LYG2 25348397 N/A physical interaction ComPPI
KIF3A MAP1LC3B2 25348397 N/A physical interaction ComPPI
KIF3A ZNF785 25348397 N/A physical interaction ComPPI
KIF3A CALHM4 25348397 N/A physical interaction ComPPI
KIF3A ALOX15B 25348397 N/A physical interaction ComPPI
KIF3A ANXA8 25348397 N/A physical interaction ComPPI
KIF3A LRRC15 25348397 N/A physical interaction ComPPI
KIF3A DSG4 25348397 N/A physical interaction ComPPI
KIF3A SERPINB5 25348397 N/A physical interaction ComPPI
KIF3A HSDL2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KIF3A DNAJC9 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KIF3A INTU 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KIF3A TULP3 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
PSME3IP1 KIF3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PADI3 KIF3A 25348397 N/A physical interaction ComPPI
HENMT1 KIF3A 25348397 N/A physical interaction ComPPI
PPP1R15A KIF3A 10631107 14525934 27898060 N/A experimental interaction detection,two hybrid HPRD,OmniPath
RPGR KIF3A 14525934 16043481 N/A experimental interaction detection HPRD
H3C15 KIF3A 24234451 30021884 physical association cross-linking study IntAct
H4C1 KIF3A 24234451 30021884 physical association cross-linking study IntAct
KIF3A PKD2 16950792 17008358 17283055 27898060 stimulant N/A OmniPath
ARRB2 KIF3A 16908539 23074268 23877428 27898060 stimulant N/A OmniPath
ARRB1 KIF3A 18497258 27898060 stimulant N/A OmniPath
CAMK2A KIF3A 24338362 25878107 27898060 N/A N/A OmniPath

Visualization










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