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GENE：LMTK2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LMTK2
FullNmae lemur tyrosine kinase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17880
EnsembleID ENSG00000164715
Uniprot Q8IWU2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LMTK2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LMTK2 GO:0001881,GO:0004672,GO:0004674,GO:0004864,GO:0005515,GO:0005524,GO:0005769,GO:0005794,GO:0005829,GO:0006468,GO:0006468,GO:0016020,GO:0018105,GO:0018107,GO:0030426,GO:0032456,GO:0033572,GO:0043025,GO:0045022,GO:0046777,GO:0048471,GO:0055037,GO:0070853,GO:0106310

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDK5R1 LMTK2 12832520 23331499 stimulation N/A SignaLink,SignaLink
CDK5 LMTK2 12832520 23331499 stimulation N/A SignaLink
LMTK2 PPP1CA 12393858 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR LMTK2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LMTK2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 LMTK2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 LMTK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LMTK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LMTK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 LMTK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 LMTK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LMTK2 15289351 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LMTK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LMTK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LMTK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LMTK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 LMTK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 LMTK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 LMTK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR LMTK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 LMTK2 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 LMTK2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000427B68 LMTK2 21572407 22012620 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005C1F22 LMTK2 21572407 22012620 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB LMTK2 21572407 22012620 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 LMTK2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004E008F LMTK2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 LMTK2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005BB0FD LMTK2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000035AC91 LMTK2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005586D0 LMTK2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA LMTK2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 LMTK2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC LMTK2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDA4 LMTK2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 LMTK2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000381CEC LMTK2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A LMTK2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 LMTK2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 LMTK2 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK5 LMTK2 22135298 phosphorylation N/A PhosphoSite
LMTK2 PPP1CA 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LMTK2 CFTR 22135298 phosphorylation N/A PhosphoSite
LMTK2 PYGB 22135298 phosphorylation N/A PhosphoSite
PPP1CA LMTK2 25361965 interaction type N/A PTMCode2
LMTK2 PPP1R2 25361965 interaction type N/A PTMCode2
PPP1R2 LMTK2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPP1CC LMTK2 24234451 24366813 25348397 26496610 28330616 association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PPP1R2B LMTK2 25348397 N/A physical interaction ComPPI
PPP1CB LMTK2 25348397 N/A physical interaction ComPPI
PTPN6 LMTK2 25348397 N/A physical interaction ComPPI
CDK5R1 LMTK2 12832520 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
PPM1A LMTK2 25348397 N/A physical interaction ComPPI
PPP1R3A LMTK2 25348397 N/A physical interaction ComPPI
PPP1CA LMTK2 25348397 N/A physical interaction ComPPI
PTPRM LMTK2 25348397 N/A physical interaction ComPPI
PTPRR LMTK2 25348397 N/A physical interaction ComPPI
PTPN12 LMTK2 25348397 N/A physical interaction ComPPI
DUSP14 LMTK2 25348397 N/A physical interaction ComPPI
CDC14A LMTK2 25348397 N/A physical interaction ComPPI
CDK5 LMTK2 25348397 N/A physical interaction ComPPI
MYO6 LMTK2 18029400 18429820 19855435 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TRIM25 LMTK2 25348397 N/A physical interaction ComPPI
CDC25C LMTK2 25348397 N/A physical interaction ComPPI
PPP1R2 LMTK2 12393858 14525934 24234451 25348397 phosphorylation reaction,physical association two hybrid,experimental interaction detection,pull down,physical interaction,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
LMTK2 SORT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LMTK2 SLC34A2 25348397 N/A physical interaction ComPPI
LMTK2 PPP3CB 25348397 N/A physical interaction ComPPI
LMTK2 PPM1F 25348397 N/A physical interaction ComPPI
LMTK2 PPM1K 25348397 N/A physical interaction ComPPI
LMTK2 ILKAP 25348397 N/A physical interaction ComPPI
LMTK2 DUSP6 25348397 N/A physical interaction ComPPI
LMTK2 DUSP19 25348397 N/A physical interaction ComPPI
LMTK2 DUSP29 25348397 N/A physical interaction ComPPI
LMTK2 STYX 25348397 N/A physical interaction ComPPI
LMTK2 PTPDC1 25348397 N/A physical interaction ComPPI
LMTK2 TPTE2 25348397 N/A physical interaction ComPPI
LMTK2 MTMR6 25348397 N/A physical interaction ComPPI
CDK5 LMTK2 12832520 22220831 27898060 inhibition,stimulant N/A OmniPath
LMTK2 PPP1CA 12202491 12393858 17202132 17283141 18250156 20889984 21331744 22220831 27898060 inhibition,stimulant N/A OmniPath
CDK5R1 LMTK2 12832520 27898060 inhibition N/A OmniPath

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