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GENE：LPCAT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LPCAT1
FullNmae lysophosphatidylcholine acyltransferase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25718
EnsembleID ENSG00000153395
Uniprot Q8NF37

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LPCAT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LPCAT1 GO:0000139,GO:0003841,GO:0003841,GO:0005509,GO:0005783,GO:0005783,GO:0005783,GO:0005789,GO:0005794,GO:0005811,GO:0005886,GO:0006654,GO:0006656,GO:0008654,GO:0016020,GO:0030163,GO:0035577,GO:0036148,GO:0036151,GO:0036151,GO:0042171,GO:0043129,GO:0045732,GO:0047144,GO:0047159,GO:0047184,GO:0047184,GO:0047191,GO:0047192,GO:0050200,GO:0060041,GO:2001246

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LPCAT1 hsa:79888 path:hsa00564 Glycerophospholipid metabolism - Homo sapiens (human)
LPCAT1 hsa:79888 path:hsa00565 Ether lipid metabolism - Homo sapiens (human)
LPCAT1 hsa:79888 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ADRB2 LPCAT1 23180781 23798571 physical association affinity chromatography technology InnateDB

Source Target Pmid Interactiontype Methods Database
AR LPCAT1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 LPCAT1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 LPCAT1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LPCAT1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC LPCAT1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
TFAP2C LPCAT1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 LPCAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LPCAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LPCAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LPCAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LPCAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LPCAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LPCAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 LPCAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 LPCAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 LPCAT1 20304954 22473208 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS0000237AF9 LPCAT1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000007FBA LPCAT1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000ED600 LPCAT1 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 LPCAT1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000021D7C8 LPCAT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000016914 LPCAT1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00004F859B LPCAT1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000018D2BE LPCAT1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A LPCAT1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 LPCAT1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F LPCAT1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 LPCAT1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 LPCAT1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 LPCAT1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F LPCAT1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000367985 LPCAT1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 LPCAT1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 LPCAT1 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HIPK4 LPCAT1 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
BBS2 LPCAT1 25348397 N/A physical interaction ComPPI
NF2 LPCAT1 25348397 N/A physical interaction ComPPI
DOCK7 LPCAT1 25348397 N/A physical interaction ComPPI
GSK3B LPCAT1 25348397 N/A physical interaction ComPPI
NTRK1 LPCAT1 25348397 N/A physical interaction ComPPI
BTRC LPCAT1 25348397 N/A physical interaction ComPPI
ILK LPCAT1 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
LAMTOR3 LPCAT1 25348397 N/A physical interaction ComPPI
CFTR LPCAT1 25348397 N/A physical interaction ComPPI
ECT2 LPCAT1 25348397 N/A physical interaction ComPPI
MDC1 LPCAT1 25348397 N/A physical interaction ComPPI
AUP1 LPCAT1 25348397 N/A physical interaction ComPPI
ATXN3 LPCAT1 25348397 N/A physical interaction ComPPI
TRIM25 LPCAT1 25348397 N/A physical interaction ComPPI
ELAVL1 LPCAT1 25348397 N/A physical interaction ComPPI
ESR1 LPCAT1 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
DIP2A LPCAT1 25348397 N/A physical interaction ComPPI
FAF2 LPCAT1 25348397 N/A physical interaction ComPPI
TES LPCAT1 25348397 N/A physical interaction ComPPI
ILF3 LPCAT1 25348397 N/A physical interaction ComPPI
TMEM216 LPCAT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MTR LPCAT1 25348397 N/A physical interaction ComPPI
RIPK4 LPCAT1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
PCK1 LPCAT1 25348397 N/A physical interaction ComPPI
SAP25 LPCAT1 25348397 N/A physical interaction ComPPI
LPCAT1 MSTO1 25348397 N/A physical interaction ComPPI
LPCAT1 SLC27A2 25348397 N/A physical interaction ComPPI
HSCB LPCAT1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct

Visualization










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