Gene Information gene info

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GENE：LPXN

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LPXN
FullNmae leupaxin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14061
EnsembleID ENSG00000110031
Uniprot O60711

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LPXN immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LPXN GO:0002102,GO:0003712,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0005925,GO:0006355,GO:0007155,GO:0007162,GO:0007165,GO:0007179,GO:0016020,GO:0016607,GO:0033628,GO:0034446,GO:0042995,GO:0043542,GO:0046872,GO:0048471,GO:0050859,GO:0050859,GO:0065003

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 LPXN 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKG LPXN 20098747 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
LPXN ITGA4 20005715 interaction type N/A PSP
LPXN PTK2 20005715 interaction type N/A PSP
LPXN PTK2B 18988627 20005715 9565592 interaction type N/A PSP,SignaLink
LPXN PTK2 20005715 20005715 21071413 21900206 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR LPXN 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LPXN 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 LPXN 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 LPXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LPXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LPXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 LPXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LPXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 LPXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 LPXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 LPXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 LPXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000040780F LPXN 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D LPXN 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF LPXN 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 LPXN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000043C1C3 LPXN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003FBC84 LPXN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C0099 LPXN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000006372A LPXN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001CC4BD LPXN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000355E82 LPXN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041FA2C LPXN 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TXLNB LPXN 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HOXA1 LPXN 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
QRICH1 LPXN 25348397 N/A physical interaction ComPPI
PAK2 LPXN 25348397 N/A physical interaction ComPPI
EDC3 LPXN 25348397 N/A physical interaction ComPPI
TGFB1 LPXN 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZNF175 LPXN 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ZNF426 LPXN 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PAK1 LPXN 25348397 N/A physical interaction ComPPI
PTK2B LPXN 14525934 25348397 9565592 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
GIT1 LPXN 25348397 N/A physical interaction ComPPI
TNS2 LPXN 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PARVA LPXN 25348397 N/A physical interaction ComPPI
DCP1B LPXN 25348397 N/A physical interaction ComPPI
TRIP6 LPXN 25348397 N/A physical interaction ComPPI
VCL LPXN 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PTPN12 LPXN 12674328 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PDLIM7 LPXN 25348397 N/A physical interaction ComPPI
MAPK6 LPXN 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AQP1 LPXN 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PCNT LPXN 25348397 N/A physical interaction ComPPI
LMO1 LPXN 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDN LPXN 25348397 N/A physical interaction ComPPI
HDAC6 LPXN 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ITGA4 LPXN 10604475 14525934 24234451 25348397 physical association affinity chromatography technology,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
LPXN LIMS1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
LPXN PHF21A 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
LPXN POM121 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
LPXN IKBKG 20098747 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
LPXN PTK2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LPXN MAP2K7 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
LPXN RUNX1T1 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LPXN SFI1 25348397 N/A physical interaction ComPPI
LPXN PLEKHN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LPXN PLEKHH2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LPXN PLSCR4 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LPXN ARHGEF6 25348397 N/A physical interaction ComPPI
LPXN GIT2 25348397 N/A physical interaction ComPPI
LPXN PSTPIP2 25348397 N/A physical interaction ComPPI
LPXN PLEKHH1 25348397 N/A physical interaction ComPPI
LPXN ARHGEF7 25348397 N/A physical interaction ComPPI
LPXN SPECC1L 25348397 N/A physical interaction ComPPI
LPXN ATXN2 25348397 N/A physical interaction ComPPI
LPXN NUP54 25348397 N/A physical interaction ComPPI
LPXN CDK5RAP2 25348397 N/A physical interaction ComPPI
LPXN RBMS1 25348397 N/A physical interaction ComPPI
LPXN CEP68 25348397 N/A physical interaction ComPPI
LPXN LIMD1 25348397 N/A physical interaction ComPPI
LPXN PCM1 25348397 N/A physical interaction ComPPI
LPXN ZNF281 25348397 N/A physical interaction ComPPI
LPXN LPP 25348397 N/A physical interaction ComPPI
LPXN CCDC6 25348397 N/A physical interaction ComPPI
LPXN MIOS 25348397 N/A physical interaction ComPPI
LPXN MIB1 25348397 N/A physical interaction ComPPI
LPXN NR3C1 25348397 N/A physical interaction ComPPI
LPXN AGXT 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LPXN WHRN 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IMP3 LPXN 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HOXC9 LPXN 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LYN LPXN 17640867 20543562 27898060 N/A N/A OmniPath
IKBKG LPXN 20098747 27898060 N/A N/A OmniPath

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