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GENE：LSM1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LSM1
FullNmae LSM1 homolog, mRNA degradation associated
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20472
EnsembleID ENSG00000175324
Uniprot O15116

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LSM1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LSM1 GO:0000290,GO:0000339,GO:0000375,GO:0000932,GO:0003723,GO:0003729,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0006397,GO:0008380,GO:0019827,GO:0030182,GO:0030424,GO:0030425,GO:0036002,GO:0043025,GO:0045665,GO:0071044,GO:1990124,GO:1990726

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LSM1 hsa:27257 path:hsa03018 RNA degradation - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR LSM1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LSM1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 LSM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LSM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LSM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LSM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC LSM1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 LSM1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003ABC4 LSM1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00002AB575 LSM1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B LSM1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 LSM1 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LSM6 LSM1 25361965 interaction type N/A PTMCode2
LSM1 LSM6 25361965 interaction type N/A PTMCode2
LSM1 SNRPD2 25361965 interaction type N/A PTMCode2
SNRPD2 LSM1 25361965 interaction type N/A PTMCode2
LSM1 LSM2 25361965 interaction type N/A PTMCode2
LSM2 LSM1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BEX5 LSM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
WASL LSM1 25348397 N/A physical interaction ComPPI
AGR3 LSM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDUFAF3 LSM1 14525934 15231747 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
SNRPF LSM1 25348397 N/A physical interaction ComPPI
LSM2 LSM1 11920408 14525934 15231747 19628699 24234451 25348397 physical association two hybrid,experimental interaction detection,molecular sieving,physical interaction,ion exchange chromatography,two hybrid array,in vitro,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
LSM3 LSM1 11920408 14525934 15231747 19628699 24234451 25348397 25416956 26871637 physical association two hybrid,experimental interaction detection,molecular sieving,physical interaction,ion exchange chromatography,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
LSM6 LSM1 11920408 14525934 15231747 19628699 24234451 25348397 physical association two hybrid,experimental interaction detection,molecular sieving,physical interaction,ion exchange chromatography,in vitro ComPPI,HPRD,IntAct
UXT LSM1 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
VPS11 LSM1 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LSM1 PSMB8 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LSM1 NARS1 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LSM1 PSMB5 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LSM1 SMN1 10851237 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
LSM1 CLIC1 14525934 14667819 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LSM1 GRHPR 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LSM1 LSM5 11920408 14525934 19628699 24234451 25348397 physical association experimental interaction detection,molecular sieving,physical interaction,ion exchange chromatography,in vitro ComPPI,HPRD,IntAct
LSM1 LSM7 11920408 14525934 19628699 24234451 25348397 physical association experimental interaction detection,molecular sieving,ion exchange chromatography,in vitro ComPPI,HPRD,IntAct
LSM1 TMEM214 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LSM1 EXOSC8 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LSM1 RRP1B 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LSM1 UPF2 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LSM1 EXOSC6 14525934 15231747 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
LSM1 HSP90AA1 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LSM1 PTPRC 25348397 N/A in vivo ComPPI
LSM1 N4BP1 25348397 N/A physical interaction ComPPI
LSM1 BCL6 16147992 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
LSM1 SNRPD3 25348397 N/A physical interaction ComPPI
LSM1 SNRPD2 25348397 N/A physical interaction ComPPI
LSM1 PRPF3 25348397 N/A physical interaction ComPPI
LSM1 PRPF4 25348397 N/A physical interaction ComPPI
LSM1 PATL1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LSM1 INPPL1 25348397 N/A physical interaction ComPPI
LSM1 NSD2 25348397 N/A physical interaction ComPPI
LSM1 HSP90AA2P 25348397 N/A physical interaction ComPPI
LSM1 MPDU1 25348397 N/A physical interaction ComPPI
LSM1 GLUD1 25348397 N/A physical interaction ComPPI
LSM1 DDX17 25348397 N/A physical interaction ComPPI
LSM1 P3H1 25348397 N/A physical interaction ComPPI
LSM1 UBE3A 25348397 N/A physical interaction ComPPI
LSM1 PCID2 25348397 N/A physical interaction ComPPI
LSM1 SNRPE 25348397 N/A physical interaction ComPPI
LSM1 XPO1 25348397 N/A physical interaction ComPPI
LSM1 FGB 25348397 N/A physical interaction ComPPI
LSM1 PAN2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LSM1 FAM136A 15231747 24234451 25348397 physical association two hybrid ComPPI,IntAct
LSM1 GSTA4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LSM1 DAPL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LSM1 MCCD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LSM1 DDIT4L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LSM1 SOWAHA 24234451 25348397 physical association inference by socio-affinity scoring ComPPI,IntAct
LSM1 EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
LSM4 LSM1 15231747 19628699 24234451 25348397 25416956 physical association two hybrid,molecular sieving,physical interaction,ion exchange chromatography,mammalian protein protein interaction trap ComPPI,IntAct
LSM1 APPBP2 10747033 10761922 10913177 17513695 18086885 18719247 19111170 19643916 22450758 23847025 24247251 27898060 N/A N/A OmniPath

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