Gene Information gene info

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GENE：MYH11

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MYH11
FullNmae myosin heavy chain 11
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7569
EnsembleID ENSG00000133392
Uniprot P35749

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MYH11 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MYH11 GO:0000146,GO:0005515,GO:0005516,GO:0005524,GO:0005737,GO:0005829,GO:0005859,GO:0006939,GO:0008307,GO:0016460,GO:0030241,GO:0031032,GO:0032982,GO:0042470,GO:0048251,GO:0051015,GO:0055013,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MYH11 hsa:4629 path:hsa04270 Vascular smooth muscle contraction - Homo sapiens (human)
MYH11 hsa:4629 path:hsa04530 Tight junction - Homo sapiens (human)
MYH11 hsa:4629 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
MYH11 hsa:4629 path:hsa04814 Motor proteins - Homo sapiens (human)
MYH11 hsa:4629 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR MYH11 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MYH11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MYH11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MYH11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MYH11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MYH11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MYH11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MYH11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
KLF5 MYH11 12707992 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002A8BC6 MYH11 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 MYH11 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 MYH11 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE MYH11 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A MYH11 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000419B5A MYH11 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000024A59E MYH11 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005485E8 MYH11 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000002103A MYH11 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF MYH11 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000EC1BE MYH11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 MYH11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 MYH11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA MYH11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 MYH11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC MYH11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C MYH11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A MYH11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B MYH11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC MYH11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB MYH11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 MYH11 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DAXX MYH11 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RALBP1 MYH11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTB MYH11 25348397 N/A physical interaction ComPPI
GTF2B MYH11 19328794 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SP1 MYH11 25348397 N/A physical interaction ComPPI
SHC1 MYH11 25348397 N/A physical interaction ComPPI
DSTN MYH11 25348397 N/A physical interaction ComPPI
GRB2 MYH11 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
JUN MYH11 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
MAPKAPK5 MYH11 14525934 25348397 9628874 N/A experimental interaction detection,in vitro ComPPI,HPRD
FLNA MYH11 25348397 N/A physical interaction ComPPI
YWHAZ MYH11 20618440 24234451 25348397 association tandem affinity purification ComPPI,IntAct
APC MYH11 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RPA1 MYH11 25348397 N/A physical interaction ComPPI
CFTR MYH11 25348397 N/A physical interaction ComPPI
C4BPA MYH11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VDAC1 MYH11 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PDHA1 MYH11 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RAD51 MYH11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPA2 MYH11 25348397 N/A physical interaction ComPPI
RPA3 MYH11 25348397 N/A physical interaction ComPPI
YWHAQ MYH11 25348397 N/A physical interaction ComPPI
SFN MYH11 25348397 N/A physical interaction ComPPI
YWHAE MYH11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTR3 MYH11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNM1L MYH11 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SVIL MYH11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MPP1 MYH11 25348397 N/A physical interaction ComPPI
GDF9 MYH11 25348397 N/A physical interaction ComPPI
CGN MYH11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYOC MYH11 25348397 N/A physical interaction ComPPI
PARK7 MYH11 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EIF3A MYH11 25348397 N/A physical interaction ComPPI
SOD1 MYH11 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
UBE2V1 MYH11 24234451 25348397 26496610 association anti tag coimmunoprecipitation ComPPI,IntAct
ARPC5 MYH11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYL12B MYH11 19328794 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MED4 MYH11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DLST MYH11 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
ACTA2 MYH11 25348397 N/A physical interaction ComPPI
MYL6 MYH11 25348397 N/A physical interaction ComPPI
FBXO25 MYH11 25348397 N/A physical interaction ComPPI
LRRC59 MYH11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO1E MYH11 25348397 N/A physical interaction ComPPI
SLX4 MYH11 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MYH11 MYO5A 25348397 N/A physical interaction ComPPI
MYH11 CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
MYH11 INF2 25348397 N/A physical interaction ComPPI
MYH11 ZNF746 25348397 N/A physical interaction ComPPI
MYH11 WRAP73 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MYH11 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
TRAF2 MYH11 24234451 30561431 association virotrap IntAct
TNFAIP3 MYH11 24234451 30561431 association virotrap IntAct
TNIP1 MYH11 24234451 30561431 association virotrap IntAct
SMC3 MYH11 24234451 30021884 physical association cross-linking study IntAct

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