GENE：NUP43
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | NUP43 |
| FullNmae | nucleoporin 43 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:21182 |
| EnsembleID | ENSG00000120253 |
| Uniprot | Q8NFH3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| NUP43 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| NUP43 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| NUP43 | GO:0000776,GO:0005515,GO:0005635,GO:0005635,GO:0005643,GO:0005654,GO:0005829,GO:0005829,GO:0006913,GO:0007059,GO:0015031,GO:0016607,GO:0031080,GO:0031080,GO:0031080,GO:0051028,GO:0051301 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| NUP43 | hsa:348995 | path:hsa03013 | Nucleocytoplasmic transport - Homo sapiens (human) |
| NUP43 | hsa:348995 | path:hsa05014 | Amyotrophic lateral sclerosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | NUP43 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | NUP43 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | NUP43 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | NUP43 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | NUP43 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | NUP43 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | NUP43 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | NUP43 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | NUP43 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | NUP43 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | NUP43 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00002FC5B0 | NUP43 | 20371350 21572407 22473208 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS0000239117 | NUP43 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000075C1E1 | NUP43 | 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A8BC6 | NUP43 | 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032AE90 | NUP43 | 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E5ECC | NUP43 | 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000137EDE | NUP43 | 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019907A | NUP43 | 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | NUP43 | 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5969 | NUP43 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000100748 | NUP43 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027352D | NUP43 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FF9C | NUP43 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001D4A78 | NUP43 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC379 | NUP43 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F4657 | NUP43 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001E3523 | NUP43 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000001EB3 | NUP43 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040780F | NUP43 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B989F | NUP43 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C85B2 | NUP43 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A7F58 | NUP43 | 21572407 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | NUP43 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | NUP43 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | NUP43 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000254A6 | NUP43 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NUP37 | NUP43 | 25361965 | interaction type | N/A | PTMCode2 |
| NUP43 | NUP37 | 25361965 | interaction type | N/A | PTMCode2 |
| NUP107 | NUP43 | 25361965 | interaction type | N/A | PTMCode2 |
| NUP43 | NUP107 | 25361965 | interaction type | N/A | PTMCode2 |
| NUP85 | NUP43 | 25361965 | interaction type | N/A | PTMCode2 |
| NUP43 | NUP85 | 25361965 | interaction type | N/A | PTMCode2 |
| NUP133 | NUP43 | 25361965 | interaction type | N/A | PTMCode2 |
| NUP43 | NUP133 | 25361965 | interaction type | N/A | PTMCode2 |
| NUP43 | NUP160 | 25361965 | interaction type | N/A | PTMCode2 |
| NUP160 | NUP43 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ISG15 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| KIF5B | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| LMNA | NUP43 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| LAGE3 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| KPNB1 | NUP43 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NUP85 | NUP43 | 24234451 24315095 25348397 26391640 | physical association | affinity chromatography technology,molecular sieving,physical interaction | ComPPI,IntAct |
| UBC | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| GUCY2D | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| MCM3AP | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| NUP98 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| XPA | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| CUL4A | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| TCP1 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| CCT7 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| RAB3GAP2 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| TP53RK | NUP43 | 23455922 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| OSGEP | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| CUL7 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| NUP153 | NUP43 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RANBP2 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| SEC13 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| NUP50 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| DDB1 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| NUP133 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| SENP2 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| AURKAIP1 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| DCTN2 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| NUP107 | NUP43 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CEP250 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| IFI16 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| KLC2 | NUP43 | 25348397 | N/A | physical interaction | ComPPI |
| NUP37 | NUP43 | 25348397 | N/A | physical interaction,in vivo | ComPPI |
| NUP43 | NUP160 | 25348397 | N/A | physical interaction | ComPPI |
| NUP43 | SEH1L | 24234451 25348397 26391640 26496610 | association,physical association | anti tag coimmunoprecipitation,molecular sieving,physical interaction | ComPPI,IntAct |
| NUP43 | CCT6B | 25348397 | N/A | physical interaction | ComPPI |
| NUP43 | TPRKB | 25348397 | N/A | physical interaction | ComPPI |
| NUP43 | KLC4 | 25348397 | N/A | physical interaction | ComPPI |
| NUP43 | CSMD3 | 25348397 | N/A | physical interaction | ComPPI |
| NUP43 | POM121 | 25348397 | N/A | physical interaction | ComPPI |
| NUP43 | RTL4 | 25348397 | N/A | physical interaction | ComPPI |
| NUP43 | TBX4 | 25348397 | N/A | physical interaction | ComPPI |
| NUP43 | RPL26L1 | 25348397 | N/A | physical interaction | ComPPI |
| NUP43 | SENP1 | 25348397 | N/A | physical interaction | ComPPI |
| NUP43 | CCT8 | 25348397 | N/A | physical interaction | ComPPI |
| NUP43 | B9D2 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| NUP43 | SPAST | 25348397 | N/A | physical interaction | ComPPI |
| NUP43 | HLA-B | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| NUP43 | AHCTF1 | 24234451 24315095 25348397 | physical association | cross-linking study,electron microscopy | ComPPI,IntAct |
| NUP43 | KSR1 | 24234451 25348397 27086506 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| NUP43 | COX14 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| IKBKG | NUP43 | 24234451 30561431 | association | virotrap | IntAct |
| ISG15 | NUP43 | 16009940 27898060 | N/A | N/A | OmniPath |