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GENE：PTP4A2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTP4A2
FullNmae protein tyrosine phosphatase 4A2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9635
EnsembleID ENSG00000184007
Uniprot Q12974

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTP4A2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTP4A2 GO:0004725,GO:0004727,GO:0005515,GO:0005634,GO:0005737,GO:0005737,GO:0005769,GO:0005829,GO:0005886,GO:0008138,GO:0016311

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PTP4A2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 PTP4A2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 PTP4A2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PTP4A2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PTP4A2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 PTP4A2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 PTP4A2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP53 PTP4A2 16980608 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PTP4A2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 PTP4A2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PTP4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PTP4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTP4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PTP4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PTP4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTP4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PTP4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PTP4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTP4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PTP4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PTP4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR PTP4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PTP4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004F4657 PTP4A2 21351259 rna interference,inhibition array technology,experimental interaction detection miRSponge
URS00000ED600 PTP4A2 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00004F4657 PTP4A2 21351259 25416803 mrna cleavage,inhibition array technology,experimental interaction detection TarBase
URS000002103A PTP4A2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000070B1D PTP4A2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C3AC1 PTP4A2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 PTP4A2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC PTP4A2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 PTP4A2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD PTP4A2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000345DEB PTP4A2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 PTP4A2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 PTP4A2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000029D793 PTP4A2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 PTP4A2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004DEA91 PTP4A2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDCD1 PTP4A2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 PTP4A2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B PTP4A2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D PTP4A2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED PTP4A2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB PTP4A2 20371350 21572407 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 PTP4A2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 PTP4A2 20371350 21572407 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C7B2B PTP4A2 21572407 23313552 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 PTP4A2 21572407 23313552 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D PTP4A2 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS0000085F64 PTP4A2 20371350 23824327 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS000076B539 PTP4A2 20371350 23824327 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS00004F24A9 PTP4A2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FHL3 PTP4A2 25348397 N/A physical interaction ComPPI
RABGGTB PTP4A2 11447212 25348397 26186194 27898060 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI,OmniPath
EPHB2 PTP4A2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RPL18A PTP4A2 25348397 N/A physical interaction ComPPI
PRDX4 PTP4A2 25348397 N/A physical interaction ComPPI
TARBP2 PTP4A2 25348397 N/A physical interaction ComPPI
SPTAN1 PTP4A2 25348397 N/A physical interaction ComPPI
USF2 PTP4A2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PTP4A2 ATF7 25348397 N/A in vitro ComPPI
PTP4A2 CNNM3 17353931 24234451 25348397 28330616 association,physical association anti bait coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PTP4A2 FNTA 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PTP4A2 PTP4A1 17353931 24234451 25348397 28330616 association,physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PTP4A2 PON2 25348397 N/A physical interaction ComPPI
PTP4A2 GNB4 25348397 N/A physical interaction ComPPI
PTP4A2 SPTBN1 25348397 N/A physical interaction ComPPI
PTP4A2 PTP4A3 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
PTP4A2 GADD45GIP1 25348397 N/A physical interaction ComPPI
PTP4A2 PRDX3 25348397 N/A physical interaction ComPPI
PTP4A2 TRIM25 25348397 N/A physical interaction ComPPI
PTP4A2 MLH1 20706999 24234451 25348397 physical association two hybrid ComPPI,IntAct
PTP4A2 PSMC5 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
PTP4A2 USP11 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
RPS19BP1 PTP4A2 25348397 N/A physical interaction ComPPI
PTP4A2 CDK2 14643450 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B036F PTP4A2 27087310 direct interaction,inhibition N/A NPInter

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