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GENE：PTPRS

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTPRS
FullNmae protein tyrosine phosphatase receptor type S
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9681
EnsembleID ENSG00000105426
Uniprot Q13332

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTPRS immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTPRS GO:0004721,GO:0004725,GO:0004725,GO:0005515,GO:0005829,GO:0005886,GO:0005886,GO:0006470,GO:0006470,GO:0008201,GO:0010977,GO:0021510,GO:0021549,GO:0021766,GO:0021987,GO:0022038,GO:0030424,GO:0030426,GO:0030517,GO:0030672,GO:0032687,GO:0032688,GO:0034164,GO:0035335,GO:0035374,GO:0042734,GO:0043204,GO:0043395,GO:0048671,GO:0048681,GO:0050804,GO:0061000,GO:0070062,GO:0090557,GO:0098685,GO:0098839,GO:0098978,GO:0099151,GO:0099537,GO:0099560,GO:0099560,GO:0099560

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PTPRS hsa:5802 path:hsa04514 Cell adhesion molecules - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 PTPRS 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 PTPRS 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC PTPRS 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 PTPRS 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C PTPRS 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA PTPRS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTPRS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PTPRS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PTPRS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTPRS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTPRS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PTPRS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTPRS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PTPRS 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000042E1F PTPRS 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007F792 PTPRS 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00001FFA8C PTPRS 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1B PTPRS 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D PTPRS 24374217 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PPFIA1 PTPRS 25361965 interaction type N/A PTMCode2
PTPRS PPFIA1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
STX11 PTPRS 25348397 N/A physical interaction ComPPI
ARRDC3 PTPRS 25348397 N/A physical interaction ComPPI
MMP3 PTPRS 25348397 N/A physical interaction ComPPI
PPFIA1 PTPRS 14525934 25348397 8524829 9624153 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TGFBR2 PTPRS 25348397 N/A physical interaction ComPPI
SETDB1 PTPRS 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UNC119 PTPRS 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TRIO PTPRS 25348397 N/A physical interaction ComPPI
FEZ1 PTPRS 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CLU PTPRS 25348397 N/A physical interaction ComPPI
NTRK1 PTPRS 25348397 N/A physical interaction ComPPI
PTPRF PTPRS 25348397 N/A physical interaction ComPPI
PTPRA PTPRS 10777529 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PFN2 PTPRS 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTPRM PTPRS 12376545 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPRS PPFIA2 14525934 25348397 9624153 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PTPRS PPFIA3 14525934 25348397 9624153 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PTPRS EGFR 10435588 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPRS PTPRE 12376545 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPRS KAT5 14525934 16169070 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,two hybrid ComPPI,HPRD,IntAct
PTPRS PTN 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTPRS UBR1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTPRS MOB4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTPRS EEF1G 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTPRS CEP126 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PTPRS RAB35 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTPRS UTP14A 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTPRS PTPRN 14525934 16273344 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,IntAct
PTPRS EIF4A2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPRS CHD3 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTPRS TUBB2A 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PTPRS PTPRD 14525934 25348397 27898060 9566880 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
PTPRS RYK 25348397 N/A physical interaction ComPPI
PTPRS FBXO6 25348397 N/A physical interaction ComPPI
PTPRS HLA-DPA1 25348397 N/A physical interaction ComPPI
PTPRS CEACAM21 25348397 N/A physical interaction ComPPI
PTPRS TMEM231 25348397 N/A physical interaction ComPPI
PTPRS GINM1 25348397 N/A physical interaction ComPPI
PTPRS TNF 25348397 N/A physical interaction ComPPI
PTPRS HEPACAM2 25348397 N/A physical interaction ComPPI
PTPRS CASKIN2 25348397 N/A physical interaction ComPPI
PTPRS NTRK3 25348397 N/A physical interaction ComPPI
PTPRS PCDH12 25348397 N/A physical interaction ComPPI
PTPRS LRRIQ1 25348397 N/A physical interaction ComPPI
PTPRS SLC39A5 25348397 N/A physical interaction ComPPI
PTPRS PCDHGB1 25348397 N/A physical interaction ComPPI
PTPRS FKBP9 25348397 N/A physical interaction ComPPI
PTPRS TNFSF8 25348397 N/A physical interaction ComPPI
PTPRS KLRG2 25348397 N/A physical interaction ComPPI
PTPRS MRAP2 25348397 N/A physical interaction ComPPI
PTPRS LIPG 25348397 N/A physical interaction ComPPI
PTPRS FCGRT 25348397 N/A physical interaction ComPPI
PTPRS CRP 25348397 N/A physical interaction ComPPI
PTPRS RUSF1 25348397 N/A physical interaction ComPPI
PTPRS MANSC1 25348397 N/A physical interaction ComPPI
PTPRS IL13RA2 25348397 N/A physical interaction ComPPI
PTPRS TMEM30B 25348397 N/A physical interaction ComPPI
PTPRS TRIM25 25348397 N/A physical interaction ComPPI
PTPRS HNRNPL 25348397 N/A physical interaction ComPPI
PTPRS SUMO2 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PTPRS PTPRS 15978577 24234451 association tox-r dimerization assay IntAct
RRBP1 PTPRS 24234451 30021884 physical association cross-linking study IntAct
CCDC47 PTPRS 24234451 30021884 physical association cross-linking study IntAct
PTPRS NTRK2 17967490 27898060 N/A N/A OmniPath
PTPRS NTRK1 17967490 27898060 N/A N/A OmniPath
PTPRS EGFR 10435588 15522239 27898060 N/A N/A OmniPath
PTPRS NTRK3 17967490 27898060 N/A N/A OmniPath
HSPG2 PTPRS 11865065 27898060 stimulant N/A OmniPath

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