GENE：SRCAP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SRCAP |
| FullNmae | Snf2 related CREBBP activator protein |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:16974 |
| EnsembleID | ENSG00000080603 |
| Uniprot | Q6ZRS2 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SRCAP | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SRCAP | GO:0000786,GO:0000812,GO:0003677,GO:0003713,GO:0004386,GO:0004402,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005794,GO:0006338,GO:0006355,GO:0006357,GO:0016604,GO:0016887,GO:0032991,GO:0042393,GO:0045893,GO:0048471,GO:0140658 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| SRCAP | hsa:10847 | path:hsa03082 | ATP-dependent chromatin remodeling - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | SRCAP | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | SRCAP | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | SRCAP | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | SRCAP | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | SRCAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | SRCAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SRCAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | SRCAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | SRCAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | SRCAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | SRCAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | SRCAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | SRCAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | SRCAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000070B1D | SRCAP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000EC1BE | SRCAP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002C0FCB | SRCAP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001C3AC1 | SRCAP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00003D5391 | SRCAP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00005651EE | SRCAP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00003CF1AD | SRCAP | 23313552 23622248 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS0000330617 | SRCAP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000F4AC3 | SRCAP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002075FA | SRCAP | 23622248 23824327 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS0000031E12 | SRCAP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000324096 | SRCAP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00003E5ECC | SRCAP | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000014F13C | SRCAP | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000279B6F | SRCAP | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AD2AA | SRCAP | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002394F5 | SRCAP | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000235862 | SRCAP | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00006097A6 | SRCAP | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002367FA | SRCAP | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000049704B | SRCAP | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000383DF4 | SRCAP | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039607D | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006372A | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004900F1 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004818BD | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005D986D | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000EF0B | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E226A | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000044FD7 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029D9F1 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006B702 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000010BD8D | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000451A1 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000035CC3E | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005481D | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FD1A | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000435A77 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021D7C8 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C1E1 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000021D08 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D2F5 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E949 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000346991 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000070CD2 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039E1E1 | SRCAP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075BDA4 | SRCAP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000060AABB | SRCAP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C4DB5 | SRCAP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D1FC | SRCAP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003B6B84 | SRCAP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000004CA3 | SRCAP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000086A4D | SRCAP | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | SRCAP | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SRCAP | ZNHIT1 | 25361965 | interaction type | N/A | PTMCode2 |
| ZNHIT1 | SRCAP | 25361965 | interaction type | N/A | PTMCode2 |
| SRCAP | DMAP1 | 25361965 | interaction type | N/A | PTMCode2 |
| DMAP1 | SRCAP | 25361965 | interaction type | N/A | PTMCode2 |
| SRCAP | CARM1 | 25361965 | interaction type | N/A | PTMCode2 |
| CARM1 | SRCAP | 25361965 | interaction type | N/A | PTMCode2 |
| SRCAP | VPS72 | 25361965 | interaction type | N/A | PTMCode2 |
| VPS72 | SRCAP | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MORF4L2 | SRCAP | 25348397 | N/A | physical interaction | ComPPI |
| ZNHIT1 | SRCAP | 15647280 16230350 24234451 25348397 | association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MRGBP | SRCAP | 25348397 | N/A | physical interaction | ComPPI |
| QPRT | SRCAP | 25348397 | N/A | physical interaction | ComPPI |
| H2BC4 | SRCAP | 25348397 | N/A | physical interaction | ComPPI |
| JUN | SRCAP | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| AR | SRCAP | 25348397 | N/A | physical interaction | ComPPI |
| CREBBP | SRCAP | 10347196 11581372 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
| EP300 | SRCAP | 25348397 | N/A | physical interaction | ComPPI |
| KAT2B | SRCAP | 11581372 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| NCOR1 | SRCAP | 11013263 24234451 25348397 | physical association | chromatography technology,physical interaction | ComPPI,IntAct |
| RUVBL1 | SRCAP | 16230350 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MORF4L1 | SRCAP | 25348397 | N/A | physical interaction | ComPPI |
| NCOA2 | SRCAP | 14500758 14525934 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| RNF168 | SRCAP | 25348397 | N/A | physical interaction | ComPPI |
| ZBTB7A | SRCAP | 24234451 25348397 26816381 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| ACTL6A | SRCAP | 15647280 24234451 25348397 | association | affinity chromatography technology | ComPPI,IntAct |
| MSN | SRCAP | 25348397 | N/A | physical interaction | ComPPI |
| CDK9 | SRCAP | 25348397 | N/A | physical interaction | ComPPI |
| PDK1 | SRCAP | 25348397 | N/A | physical interaction | ComPPI |
| CARM1 | SRCAP | 14500758 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
| SRCAP | ATG9A | 14525934 16169070 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| SRCAP | RUVBL2 | 16230350 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SRCAP | DMAP1 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | KAT5 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | H2AZ1 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | VPS72 | 15647280 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SRCAP | CFDP1 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | SAFB2 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | HECW2 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | OBSL1 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | CARD8 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | ACTR6 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | H2BC1 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | YEATS4 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | H2BC11 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | MAU2 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | NUF2 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | DIS3L | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | P4HA3 | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | NFATC2IP | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | ACTBL2 | 25348397 | N/A | physical interaction | ComPPI |
| SARNP | SRCAP | 25348397 | N/A | physical interaction | ComPPI |
| IK | SRCAP | 25348397 | N/A | physical interaction | ComPPI |
| SRCAP | AR | 20432434 27898060 | stimulant | N/A | OmniPath |