Gene Information gene info

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GENE：SRD5A3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SRD5A3
FullNmae steroid 5 alpha-reductase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25812
EnsembleID ENSG00000128039
Uniprot Q9H8P0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SRD5A3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SRD5A3 GO:0003865,GO:0003865,GO:0005783,GO:0005783,GO:0005789,GO:0006488,GO:0006488,GO:0006489,GO:0006702,GO:0016095,GO:0016095,GO:0016628,GO:0016628,GO:0019348,GO:0019408,GO:0047751,GO:0102389

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SRD5A3 hsa:79644 path:hsa00140 Steroid hormone biosynthesis - Homo sapiens (human)
SRD5A3 hsa:79644 path:hsa00510 N-Glycan biosynthesis - Homo sapiens (human)
SRD5A3 hsa:79644 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SRD5A3 20610535 22194926 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 SRD5A3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SRD5A3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SRD5A3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SRD5A3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SRD5A3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SRD5A3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SRD5A3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SRD5A3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SRD5A3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SRD5A3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SRD5A3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001A405B SRD5A3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CF056 SRD5A3 23313552 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00002AB575 SRD5A3 23313552 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000007340 SRD5A3 23313552 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000057FDB8 SRD5A3 23313552 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003CC709 SRD5A3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002367FA SRD5A3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000160683 SRD5A3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000019907A SRD5A3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000137EDE SRD5A3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00006097A6 SRD5A3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000475586 SRD5A3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005485E8 SRD5A3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000036B845 SRD5A3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000209F04 SRD5A3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000052EA98 SRD5A3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000ECE9C SRD5A3 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HNRNPL SRD5A3 25348397 N/A physical interaction ComPPI
ADK SRD5A3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct

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