GENE:SWAP70
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SWAP70 |
| FullNmae | switching B cell complex subunit SWAP70 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17070 |
| EnsembleID | ENSG00000133789 |
| Uniprot | Q9UH65 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SWAP70 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| SWAP70 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SWAP70 | GO:0003677,GO:0005085,GO:0005509,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005886,GO:0007204,GO:0015629,GO:0030027,GO:0030835,GO:0032233,GO:0032880,GO:0033633,GO:0045190,GO:0045296,GO:0051017,GO:0051056,GO:0060754,GO:1902309 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | SWAP70 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | SWAP70 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | SWAP70 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | SWAP70 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | SWAP70 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | SWAP70 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | SWAP70 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SWAP70 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | SWAP70 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | SWAP70 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | SWAP70 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | SWAP70 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | SWAP70 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | SWAP70 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | SWAP70 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | SWAP70 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | SWAP70 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00004F4657 | SWAP70 | 21351259 21360565 | rna interference,inhibition | array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr | miRSponge |
| URS00004F4657 | SWAP70 | 21351259 21360565 25416803 | mrna cleavage,inhibition | array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS00002DD349 | SWAP70 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC864 | SWAP70 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000183BED | SWAP70 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000315338 | SWAP70 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021D7C8 | SWAP70 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000004CA3 | SWAP70 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003CF1AD | SWAP70 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NPM1 | SWAP70 | 25348397 | N/A | physical interaction | ComPPI |
| IGHG1 | SWAP70 | 10681448 25348397 27898060 | N/A | in vitro | ComPPI,OmniPath |
| SET | SWAP70 | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | PARP1 | 14525934 25348397 9642267 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| SWAP70 | CELSR3 | 12421765 14525934 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| SWAP70 | NCL | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | RANBP3 | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | SUPT5H | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | CORO1B | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | CRMP1 | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | CUL1 | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | FAF1 | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | FARSB | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | GANAB | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | JMJD6 | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | OSBP | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | PACSIN2 | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | PAICS | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | PPP2R5C | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | XRCC6 | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | ZRANB2 | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | SCLT1 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| SWAP70 | CDH1 | 25348397 | N/A | physical interaction | ComPPI |
| SWAP70 | CANX | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| SWAP70 | EZR | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| SWAP70 | GSK3B | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| ATP6V1B2 | SWAP70 | 25348397 | N/A | physical interaction | ComPPI |
| HSP90B1 | SWAP70 | 24234451 30021884 | physical association | cross-linking study | IntAct |
