GENE:USP12
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | USP12 |
| FullNmae | ubiquitin specific peptidase 12 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:20485 |
| EnsembleID | ENSG00000152484 |
| Uniprot | O75317 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| USP12 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| USP12 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| USP12 | GO:0004197,GO:0004843,GO:0004843,GO:0004843,GO:0005515,GO:0005575,GO:0005634,GO:0005654,GO:0005829,GO:0016579,GO:0016579,GO:0046872 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | USP12 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA1 | USP12 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | USP12 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000508C13 | USP12 | 15685193 25416803 | mrna cleavage,inhibition | array technology,array technology,experimental interaction detection | TarBase |
| URS00000F31F4 | USP12 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | USP12 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000EC1BE | USP12 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000239117 | USP12 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00005FDE70 | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B0F6 | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000015A0D9 | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000047A8F | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000214763 | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000001A7A | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E728C | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LAT | USP12 | 25348397 | N/A | physical interaction | ComPPI |
| CBLB | USP12 | 25348397 | N/A | physical interaction | ComPPI |
| NOTCH1 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
| TRAT1 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
| GRB2 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
| AR | USP12 | 24056413 25216524 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| ZAP70 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
| UBC | USP12 | 25348397 | N/A | physical interaction | ComPPI |
| RAD51AP1 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| H2BC21 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
| WDR77 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
| ITCH | USP12 | 22778262 25348397 26811477 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| GORASP1 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
| PAIP1 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MMP2 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| UCHL5 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HSPB9 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
| USP39 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| H2AC20 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
| NUP160 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DMWD | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| APP | USP12 | 25348397 | N/A | physical interaction | ComPPI |
| PHLPP1 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| USP46 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| WDR48 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| USP12 | DHX8 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| USP12 | PHLPP2 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| USP12 | RNF19B | 25348397 | N/A | physical interaction | ComPPI |
| ILF3 | USP12 | 24234451 30021884 | physical association | cross-linking study | IntAct |
