GENE:USP12
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | USP12 |
FullNmae | ubiquitin specific peptidase 12 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:20485 |
EnsembleID | ENSG00000152484 |
Uniprot | O75317 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
USP12 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
USP12 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
USP12 | GO:0004197,GO:0004843,GO:0004843,GO:0004843,GO:0005515,GO:0005575,GO:0005634,GO:0005654,GO:0005829,GO:0016579,GO:0016579,GO:0046872 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | USP12 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
GATA1 | USP12 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | USP12 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | USP12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000508C13 | USP12 | 15685193 25416803 | mrna cleavage,inhibition | array technology,array technology,experimental interaction detection | TarBase |
URS00000F31F4 | USP12 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000B59A2 | USP12 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000EC1BE | USP12 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000239117 | USP12 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00005FDE70 | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000075B0F6 | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000015A0D9 | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000047A8F | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000214763 | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000001A7A | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00002E728C | USP12 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
LAT | USP12 | 25348397 | N/A | physical interaction | ComPPI |
CBLB | USP12 | 25348397 | N/A | physical interaction | ComPPI |
NOTCH1 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
TRAT1 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
GRB2 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
AR | USP12 | 24056413 25216524 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
ZAP70 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
UBC | USP12 | 25348397 | N/A | physical interaction | ComPPI |
RAD51AP1 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
H2BC21 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
WDR77 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
ITCH | USP12 | 22778262 25348397 26811477 27898060 | N/A | physical interaction | ComPPI,OmniPath |
GORASP1 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
PAIP1 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MMP2 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
UCHL5 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
HSPB9 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
USP39 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
H2AC20 | USP12 | 25348397 | N/A | physical interaction | ComPPI |
NUP160 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
DMWD | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
APP | USP12 | 25348397 | N/A | physical interaction | ComPPI |
PHLPP1 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
USP46 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
WDR48 | USP12 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
USP12 | DHX8 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
USP12 | PHLPP2 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
USP12 | RNF19B | 25348397 | N/A | physical interaction | ComPPI |
ILF3 | USP12 | 24234451 30021884 | physical association | cross-linking study | IntAct |