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GENE：DNAJC5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DNAJC5
FullNmae DnaJ heat shock protein family (Hsp40) member C5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16235
EnsembleID ENSG00000101152
Uniprot Q9H3Z4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DNAJC5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DNAJC5 GO:0005515,GO:0005739,GO:0005765,GO:0005794,GO:0005829,GO:0005886,GO:0005886,GO:0006887,GO:0016020,GO:0016020,GO:0016020,GO:0016079,GO:0030672,GO:0031594,GO:0035577,GO:0035579,GO:0042470,GO:0042584,GO:0043008,GO:0043231,GO:0043231,GO:0043524,GO:0045055,GO:0051402,GO:0061077,GO:0061202,GO:0098693,GO:0098793

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DNAJC5 hsa:80331 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR DNAJC5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DNAJC5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DNAJC5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA DNAJC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DNAJC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DNAJC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DNAJC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DNAJC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DNAJC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000DDD35 DNAJC5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000183BED DNAJC5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000041CB9C DNAJC5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EED18 DNAJC5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000001EB3 DNAJC5 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA DNAJC5 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
PRKACA DNAJC5 11604405 14525934 14997482 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
VCL DNAJC5 25348397 N/A physical interaction ComPPI
CFTR DNAJC5 12039948 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
VAMP7 DNAJC5 14525934 15610015 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
HSPA4 DNAJC5 25348397 N/A physical interaction ComPPI
ATP6V1B1 DNAJC5 25348397 N/A physical interaction ComPPI
ECE1 DNAJC5 25348397 N/A physical interaction ComPPI
TRIM25 DNAJC5 25348397 N/A physical interaction ComPPI
STUB1 DNAJC5 25348397 N/A physical interaction ComPPI
DNAJC5 PTGFR 25348397 N/A physical interaction ComPPI
DNAJC5 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CADPS DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
AGFG1 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
AP2B1 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
LIN7A DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
FCHO1 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
ERC1 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
ZDHHC17 DNAJC5 24234451 29997244 colocalization,physical association bioluminescence resonance energy transfer,confocal microscopy,luminescence based mammalian interactome mapping IntAct
SNAP91 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
DNAJC5 RBSN 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
SNAP29 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
SNCA DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
SH3GL3 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
GRM8 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
SCAMP1 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
SCAMP5 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
CASK DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
NECAP1 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
LIN7C DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
NUMB DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
RABGEF1 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
PPFIA1 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
PPFIA4 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
CADM1 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
SYP DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
SYT1 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
SYT5 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
VAMP2 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
VAMP3 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
VAMP4 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
CGB3 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
DNAJC5 CD2 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
DNAJC5 STX6 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
DNAJC5 STX12 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
STX3 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
NRXN3 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
EFNB1 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
DNAJC5 ARHGEF15 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
DNAJC5 VAMP1 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
STX7 DNAJC5 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
DNAJC5 HGS 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
AP2S1 DNAJC5 24234451 29997244 physical association luminescence based mammalian interactome mapping IntAct
SLC17A7 DNAJC5 24234451 29997244 physical association luminescence based mammalian interactome mapping IntAct
AP2A1 DNAJC5 24234451 29997244 physical association luminescence based mammalian interactome mapping IntAct
DNAJC5 FAS 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
DNAJC5 HBA1 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
DNAJC5 PRRC2B 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
DNAJC5 BTC 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
DNAJC5 PSMD12 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
DNAJC5 SLC6A1 24234451 29997244 physical association bioluminescence resonance energy transfer,luminescence based mammalian interactome mapping IntAct
DNAJC5 NECTIN2 24234451 29997244 physical association bioluminescence resonance energy transfer,luminescence based mammalian interactome mapping IntAct
DNAJC5 KHDC4 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
DNAJC5 PSTPIP2 24234451 29997244 physical association luminescence based mammalian interactome mapping IntAct
DNAJC5 L3MBTL2 24234451 29997244 physical association luminescence based mammalian interactome mapping IntAct
DNAJC5 BEST1 24234451 29997244 physical association luminescence based mammalian interactome mapping IntAct
DNAJC5 FANCC 24234451 29997244 physical association luminescence based mammalian interactome mapping IntAct
SLC17A8 DNAJC5 24234451 29997244 physical association luminescence based mammalian interactome mapping IntAct
SLC32A1 DNAJC5 24234451 29997244 physical association luminescence based mammalian interactome mapping IntAct
DNAJC5 SKP2 24234451 29997244 physical association luminescence based mammalian interactome mapping IntAct
DNAJC5 TRAF6 24234451 29997244 physical association luminescence based mammalian interactome mapping IntAct
SLC18A3 DNAJC5 24234451 29997244 physical association luminescence based mammalian interactome mapping IntAct
PRKACA DNAJC5 11604405 14997482 17322306 17924679 18088087 18452278 18669648 18707149 18767875 18951872 19651622 19664995 20058876 20068231 20166139 20230923 24956274 27898060 N/A N/A OmniPath
DNAJC5 CACNA1B 11086994 27898060 inhibition N/A OmniPath

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