Gene Information gene info

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GENE：AGRN

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AGRN
FullNmae agrin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:329
EnsembleID ENSG00000188157
Uniprot O00468

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AGRN immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AGRN GO:0002162,GO:0005200,GO:0005201,GO:0005509,GO:0005515,GO:0005576,GO:0005604,GO:0005796,GO:0005886,GO:0007010,GO:0007165,GO:0007213,GO:0007528,GO:0033691,GO:0035374,GO:0043113,GO:0043113,GO:0043113,GO:0043202,GO:0043236,GO:0043395,GO:0043547,GO:0045162,GO:0045202,GO:0045887,GO:0045944,GO:0050808,GO:0051491,GO:0062023,GO:0062023,GO:0062023,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AGRN hsa:375790 path:hsa04512 ECM-receptor interaction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AGRN MUSK 18848351 23331499 stimulation N/A SignaLink,SignaLink

Source Target Pmid Interactiontype Methods Database
SMARCA4 AGRN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AGRN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AGRN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS AGRN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A AGRN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF AGRN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR AGRN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 AGRN 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 AGRN 17881434 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000CC005 AGRN 24398324 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MUSK AGRN 25361965 interaction type N/A PTMCode2
AGRN MUSK 25361965 interaction type N/A PTMCode2
DAG1 AGRN 25361965 interaction type N/A PTMCode2
AGRN DAG1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PDIA3 AGRN 17170699 24234451 25348397 disulfide bond anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBG1 AGRN 25348397 N/A physical interaction ComPPI
UBC AGRN 25348397 N/A physical interaction ComPPI
GFI1B AGRN 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CACNA1A AGRN 21078624 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
DAG1 AGRN 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
OS9 AGRN 25348397 N/A physical interaction ComPPI
OLFM3 AGRN 25348397 N/A physical interaction ComPPI
SKI AGRN 25348397 N/A physical interaction ComPPI
ATXN7 AGRN 21078624 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
CRP AGRN 25348397 N/A physical interaction ComPPI
CAMKV AGRN 25348397 N/A physical interaction ComPPI
AGRN ATN1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
AGRN MOV10 25348397 N/A physical interaction ComPPI
AGRN NXF1 25348397 N/A physical interaction ComPPI
AGRN ZFP41 25348397 N/A physical interaction ComPPI
AGRN PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
AGRN MUSK 27898060 8653787 N/A N/A OmniPath
AGRN LRP4 18848351 27898060 N/A N/A OmniPath
AGRN ATP1A3 16630822 27898060 N/A N/A OmniPath

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