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GENE：TGIF1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TGIF1
FullNmae TGFB induced factor homeobox 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11776
EnsembleID ENSG00000177426
Uniprot Q15583

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TGIF1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TGIF1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TGIF1 GO:0000122,GO:0000122,GO:0000122,GO:0000785,GO:0000978,GO:0000978,GO:0000981,GO:0001227,GO:0001227,GO:0001227,GO:0003700,GO:0005515,GO:0005654,GO:0005654,GO:0009410,GO:0010629,GO:0070410,GO:0071363,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TGIF1 hsa:7050 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TGIF1 SOX3 22293114 23180781 physical association electrophoretic mobility supershift assay InnateDB
TGIF1 WWP1 15359284 18511908 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR TGIF1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TGIF1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 TGIF1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TGIF1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 TGIF1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 TGIF1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TGIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TGIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TGIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TGIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TGIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TGIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TGIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TGIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TGIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 TGIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TGIF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HDAC4 TGIF1 17610967 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D TGIF1 19906824 rna interference,inhibition western blot miRSponge
URS000009262D TGIF1 19906824 25416803 mrna cleavage,inhibition western blot TarBase
URS000072B4C8 TGIF1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 TGIF1 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 TGIF1 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 TGIF1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D TGIF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF TGIF1 23592263 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F TGIF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 TGIF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC TGIF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD TGIF1 23592263 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000572E11 TGIF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000028D811 TGIF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED TGIF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 TGIF1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000000E601 TGIF1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 TGIF1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 TGIF1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D TGIF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 TGIF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C TGIF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 TGIF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002E92A8 TGIF1 25416803 25979625 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000183BED TGIF1 25416803 27306475 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000007F792 TGIF1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 TGIF1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 TGIF1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000355E82 TGIF1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CTBP1 TGIF1 25361965 interaction type N/A PTMCode2
TGIF1 CTBP1 25361965 interaction type N/A PTMCode2
PML TGIF1 25361965 interaction type N/A PTMCode2
TGIF1 PML 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
STK16 TGIF1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MDFI TGIF1 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SMAD1 TGIF1 25348397 N/A physical interaction ComPPI
MAPK1 TGIF1 11226163 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MAPK3 TGIF1 11226163 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
JUN TGIF1 11371641 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
AR TGIF1 11682623 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SMAD2 TGIF1 10199400 11371641 14525934 18511908 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TGIF1 CTBP1 10995736 14525934 24234451 25348397 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
TGIF1 EEF1A1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TGIF1 CTBP2 14525934 16189514 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
TGIF1 MED31 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TGIF1 SIN3A 11416139 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
TGIF1 LRIF1 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
TGIF1 IRF2BP1 14525934 18511908 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
TGIF1 PML 14525934 18511908 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,fluorescence microscopy,in vivo ComPPI,HPRD,IntAct
TGIF1 WWP1 14525934 18511908 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TGIF1 MKKS 25348397 N/A physical interaction ComPPI
TGIF1 SDAD1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TGIF1 HDAC1 11226163 14525934 18511908 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
TGIF1 SMAD3 25348397 N/A physical interaction ComPPI
TGIF1 FOXH1 25348397 N/A physical interaction ComPPI
TGIF1 EEF1A1P5 25348397 N/A physical interaction ComPPI
TGIF1 A2M 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TGIF1 ELAVL1 25348397 N/A physical interaction ComPPI
TGIF1 APP 25348397 N/A physical interaction ComPPI
TGIF1 RIF1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TGIF1 LGALS8 18511908 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,fluorescence microscopy ComPPI,IntAct
TGIF1 AXIN2 24234451 25348397 25873176 association,physical association anti bait coimmunoprecipitation,two hybrid ComPPI,IntAct
TGIF1 AXIN1 24234451 25348397 25873176 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
TGIF1 CTNNB1 24234451 25348397 25873176 colocalization,association chromatin immunoprecipitation assay,fluorescence microscopy ComPPI,IntAct
HMGB1 TGIF1 11748221 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TCF7L2 TGIF1 24234451 25873176 association chromatin immunoprecipitation assay IntAct
MAPK3 TGIF1 11226163 27898060 N/A N/A OmniPath
MAPK1 TGIF1 11226163 27898060 N/A N/A OmniPath
TGIF1 WWP1 15359284 18511908 1851191 27898060 stimulant N/A OmniPath

Visualization










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