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GENE：LTB4R

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LTB4R
FullNmae leukotriene B4 receptor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6713
EnsembleID ENSG00000213903
Uniprot Q15722

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LTB4R immunogenic 36579538 Through literature reviews, a total of 108 ICD-related genes were identified (Supplement Table S1). retulator signature

Go Annotation:

GeneSymbol Go id
LTB4R GO:0000166,GO:0001632,GO:0004974,GO:0005886,GO:0006936,GO:0006954,GO:0006955,GO:0007186,GO:0007200,GO:0007218,GO:0008528,GO:0061737

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LTB4R hsa:1241 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 LTB4R 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 LTB4R 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LTB4R 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LTB4R 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LTB4R 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LTB4R 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 LTB4R 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 LTB4R 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR LTB4R 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
GRK6 LTB4R 22135298 phosphorylation N/A PhosphoSite
GNA15 LTB4R 25361965 interaction type N/A PTMCode2
LTB4R GNA15 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
YWHAG LTB4R 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GRK6 LTB4R 12077128 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GNA15 LTB4R 25348397 27898060 9742207 N/A in vitro,in vivo ComPPI,OmniPath
LTB4R GNAI2 17139258 25348397 27898060 N/A physical interaction ComPPI,OmniPath
LTB4R CYBB 25348397 N/A physical interaction ComPPI
GRK6 LTB4R 12077128 20058876 22707565 27898060 N/A N/A OmniPath

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