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GENE：CYP51A1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CYP51A1
FullNmae cytochrome P450 family 51 subfamily A member 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2649
EnsembleID ENSG00000001630
Uniprot Q16850

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CYP51A1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CYP51A1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CYP51A1 GO:0005506,GO:0005789,GO:0006694,GO:0006695,GO:0008398,GO:0008398,GO:0016020,GO:0016125,GO:0016125,GO:0016491,GO:0020037,GO:0042177,GO:0050709,GO:1900222

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CYP51A1 hsa:1595 path:hsa00100 Steroid biosynthesis - Homo sapiens (human)
CYP51A1 hsa:1595 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CYP51A1 EGR1 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA1 CYP51A1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CYP51A1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 CYP51A1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CYP51A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CYP51A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CYP51A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CYP51A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CYP51A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CYP51A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CYP51A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 CYP51A1 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 CYP51A1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS0000237AF9 CYP51A1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 CYP51A1 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000041CB9C CYP51A1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075C4B1 CYP51A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 CYP51A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000A9FB9 CYP51A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 CYP51A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 CYP51A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000032835F CYP51A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 CYP51A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000939AF CYP51A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 CYP51A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000027464B CYP51A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001DC1D3 CYP51A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 CYP51A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F CYP51A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E CYP51A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000156390 CYP51A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 CYP51A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 CYP51A1 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003AA845 CYP51A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D CYP51A1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002152A8 CYP51A1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000019907A CYP51A1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000137EDE CYP51A1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000032AE90 CYP51A1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000237E04 CYP51A1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000B989F CYP51A1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A760 CYP51A1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003E5ECC CYP51A1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C1E1 CYP51A1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 CYP51A1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CYP51A1 LBR 25361965 interaction type N/A PTMCode2
LBR CYP51A1 25361965 interaction type N/A PTMCode2
CYP51A1 TM7SF2 25361965 interaction type N/A PTMCode2
TM7SF2 CYP51A1 25361965 interaction type N/A PTMCode2
CYP51A1 DHCR7 25361965 interaction type N/A PTMCode2
DHCR7 CYP51A1 25361965 interaction type N/A PTMCode2
CYP51A1 LSS 25361965 interaction type N/A PTMCode2
LSS CYP51A1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
YES1 CYP51A1 25348397 N/A physical interaction ComPPI
HRAS CYP51A1 25348397 N/A physical interaction ComPPI
PTPRO CYP51A1 25348397 N/A physical interaction ComPPI
EVC2 CYP51A1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ELAVL1 CYP51A1 25348397 N/A physical interaction ComPPI
SPINT2 CYP51A1 25348397 N/A physical interaction ComPPI
CCNY CYP51A1 25348397 N/A physical interaction ComPPI
RRP1B CYP51A1 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PTGER3 CYP51A1 25348397 N/A physical interaction ComPPI
ETS1 CYP51A1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
FAM189A2 CYP51A1 25348397 N/A physical interaction ComPPI
SRPRB CYP51A1 25348397 N/A physical interaction ComPPI
EVA1C CYP51A1 25348397 N/A physical interaction ComPPI
TSPAN17 CYP51A1 25348397 N/A physical interaction ComPPI
CGRRF1 CYP51A1 25348397 N/A physical interaction ComPPI
ZNF420 CYP51A1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ACTBL2 CYP51A1 25348397 N/A physical interaction ComPPI
POTEI CYP51A1 25348397 N/A physical interaction ComPPI
CYP51A1 MCOLN3 25348397 N/A physical interaction ComPPI
CYP51A1 KCNK16 25348397 N/A physical interaction ComPPI
CYP51A1 TREML2 25348397 N/A physical interaction ComPPI
CYP51A1 HTR3E 25348397 N/A physical interaction ComPPI
CYP51A1 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CYP51A1 PCDHA3 25348397 N/A physical interaction ComPPI
CYP51A1 PCDHGB4 25348397 N/A physical interaction ComPPI
HSCB CYP51A1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct

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