Gene Information gene info

  1. Home

GENE：SOCS5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SOCS5
FullNmae suppressor of cytokine signaling 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16852
EnsembleID ENSG00000171150
Uniprot O75159

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SOCS5 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SOCS5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SOCS5 GO:0005154,GO:0005515,GO:0005829,GO:0005942,GO:0007173,GO:0007175,GO:0007259,GO:0009968,GO:0016567,GO:0019221,GO:0030971,GO:0032436,GO:0032715,GO:0035556,GO:0045627,GO:0045629,GO:0046854,GO:0046935,GO:0050728,GO:0071404,GO:0071638,GO:0097699

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SOCS5 hsa:9655 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
SOCS5 hsa:9655 path:hsa04917 Prolactin signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGFR SOCS5 15590694 23180781 physical association anti tag coimmunoprecipitation InnateDB
SOCS5 ELOB 15590694 23180781 physical association anti tag coimmunoprecipitation InnateDB
SOCS5 ELOC 15590694 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP SOCS5 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
AR SOCS5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SOCS5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 SOCS5 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SOCS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SOCS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SOCS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SOCS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SOCS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SOCS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SOCS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SOCS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SOCS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SOCS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SOCS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SOCS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D SOCS5 17991735 rna interference,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr miRSponge
URS000009262D SOCS5 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS00001EFEC1 SOCS5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 SOCS5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 SOCS5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 SOCS5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C SOCS5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D SOCS5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 SOCS5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A SOCS5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 SOCS5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B2B SOCS5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000018E72A SOCS5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED SOCS5 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 SOCS5 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000019F055 SOCS5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 SOCS5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075C3F6 SOCS5 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000042935A SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000AA464 SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C SOCS5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A SOCS5 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001270D3 SOCS5 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 SOCS5 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000034979B SOCS5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA SOCS5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 SOCS5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000568FF8 SOCS5 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000209F04 SOCS5 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
IL4R SOCS5 25361965 interaction type N/A PTMCode2
SOCS5 IL4R 25361965 interaction type N/A PTMCode2
EGFR SOCS5 25361965 interaction type N/A PTMCode2
SOCS5 EGFR 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CUL5 SOCS5 25348397 N/A physical interaction ComPPI
DCUN1D1 SOCS5 25348397 N/A physical interaction ComPPI
KIT SOCS5 14525934 14707129 24234451 24728074 25348397 N/A experimental interaction detection,fluorescence polarization spectroscopy,in vivo ComPPI,HPRD,IntAct
CASP3 SOCS5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBC SOCS5 25348397 N/A physical interaction ComPPI
MET SOCS5 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
EGFR SOCS5 14525934 15695332 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ELOC SOCS5 16643902 24234451 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TRIM25 SOCS5 25348397 N/A physical interaction ComPPI
ALK SOCS5 25348397 N/A physical interaction ComPPI
IL4R SOCS5 12242343 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SOCS5 APP 25348397 N/A physical interaction ComPPI
SOCS5 TMBIM1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS5 EGFR 15590694 15695332 27898060 N/A N/A OmniPath
EGFR SOCS5 15590694 15695332 27898060 N/A N/A OmniPath
SOCS5 APP 21244100 21832049 27898060 N/A N/A OmniPath
APP SOCS5 21244100 21832049 27898060 N/A N/A OmniPath
SOCS5 ELOC 15590694 16643902 19385048 27898060 N/A N/A OmniPath

Visualization










  Return