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GENE：C9

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol C9
FullNmae complement C9
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1358
EnsembleID ENSG00000113600
Uniprot P02748

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
C9 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
C9 GO:0001906,GO:0005515,GO:0005576,GO:0005579,GO:0005579,GO:0005579,GO:0005615,GO:0005615,GO:0005886,GO:0005886,GO:0006956,GO:0006957,GO:0006958,GO:0031640,GO:0044218,GO:0050778,GO:0051260,GO:0070062,GO:0072562

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
C9 hsa:735 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)
C9 hsa:735 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
C9 hsa:735 path:hsa05020 Prion disease - Homo sapiens (human)
C9 hsa:735 path:hsa05146 Amoebiasis - Homo sapiens (human)
C9 hsa:735 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
C9 hsa:735 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 C9 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 C9 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 C9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF C9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 C9 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
C9 CD59 1377690 14525934 25348397 7523406 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
C9 CLU 25348397 N/A physical interaction,in vitro ComPPI
C9 FN1 25348397 N/A physical interaction ComPPI
C9 LAMTOR5 25348397 N/A physical interaction ComPPI
C9 APOE 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00009C1B53 C9 27087310 direct interaction,inhibition N/A NPInter

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