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GENE：GRIA3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GRIA3
FullNmae glutamate ionotropic receptor AMPA type subunit 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4573
EnsembleID ENSG00000125675
Uniprot P42263

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GRIA3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GRIA3 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GRIA3 GO:0001540,GO:0004971,GO:0004971,GO:0005886,GO:0005886,GO:0007215,GO:0030666,GO:0032281,GO:0032281,GO:0034220,GO:0035235,GO:0035249,GO:0043197,GO:0050804,GO:0060078,GO:0098688,GO:0098839,GO:0099505,GO:0099507,GO:0099507,GO:0099507,GO:1904315

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GRIA3 hsa:2892 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
GRIA3 hsa:2892 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)
GRIA3 hsa:2892 path:hsa04713 Circadian entrainment - Homo sapiens (human)
GRIA3 hsa:2892 path:hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human)
GRIA3 hsa:2892 path:hsa04724 Glutamatergic synapse - Homo sapiens (human)
GRIA3 hsa:2892 path:hsa04728 Dopaminergic synapse - Homo sapiens (human)
GRIA3 hsa:2892 path:hsa04730 Long-term depression - Homo sapiens (human)
GRIA3 hsa:2892 path:hsa05016 Huntington disease - Homo sapiens (human)
GRIA3 hsa:2892 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
GRIA3 hsa:2892 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
GRIA3 hsa:2892 path:hsa05031 Amphetamine addiction - Homo sapiens (human)
GRIA3 hsa:2892 path:hsa05033 Nicotine addiction - Homo sapiens (human)
GRIA3 hsa:2892 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DLG4 GRIA3 20005715 interaction type N/A PSP
GRIP1 GRIA3 20005715 interaction type N/A PSP
SDCBP GRIA3 20005715 interaction type N/A PSP
SQSTM1 GRIA3 20005715 interaction type N/A PSP
SQSTM1 GRIA3 18988627 19004011 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR GRIA3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 GRIA3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 GRIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GRIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GRIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GRIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GRIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GRIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GRIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
DLG4 GRIA3 25348397 N/A physical interaction ComPPI
PICK1 GRIA3 10027300 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
LYN GRIA3 14525934 25348397 9892356 N/A experimental interaction detection,in vivo ComPPI,HPRD
GRIA3 NSF 14525934 25348397 9697855 N/A two hybrid,two hybrid ComPPI,HPRD
GRIA3 SDCBP 11891216 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
GRIA3 GRIA2 14525934 14687553 17989220 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
GRIA3 GRIP2 25348397 N/A two hybrid ComPPI
GRIA3 SQSTM1 14525934 19004011 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
GRIA3 GRIP1 25348397 N/A physical interaction ComPPI
GRIA3 ADRB2 25348397 N/A physical interaction ComPPI
GRIA3 GRIA4 25348397 N/A physical interaction ComPPI
GRIA3 GLRB 25348397 N/A physical interaction ComPPI
GRIA3 CCPG1 25348397 N/A physical interaction ComPPI
GRIA3 CLTCL1 25348397 N/A physical interaction ComPPI
GRIA3 DNAJB9 25348397 N/A physical interaction ComPPI
GRIA3 GLB1L2 25348397 N/A physical interaction ComPPI
GRIA3 SEMA4F 25348397 N/A physical interaction ComPPI
GRIA3 DIPK1A 25348397 N/A physical interaction ComPPI
GRIA3 ALG9 25348397 N/A physical interaction ComPPI
GRIA3 TMPPE 25348397 N/A physical interaction ComPPI
GRIA3 LMF2 25348397 N/A physical interaction ComPPI
GRIA3 METAP2 25348397 N/A physical interaction ComPPI
GRIA3 HLA-F 25348397 N/A physical interaction ComPPI
GRIA3 EIF2AK3 25348397 N/A physical interaction ComPPI
PPM1G GRIA3 14525934 14663150 N/A experimental interaction detection HPRD
GZMB GRIA3 11160179 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath

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