Gene Information gene info

  1. Home

GENE：INSIG2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol INSIG2
FullNmae insulin induced gene 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20452
EnsembleID ENSG00000125629
Uniprot Q9Y5U4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
INSIG2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
INSIG2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
INSIG2 GO:0005515,GO:0005783,GO:0005783,GO:0005789,GO:0005789,GO:0006641,GO:0006695,GO:0006695,GO:0008142,GO:0010894,GO:0032869,GO:0032933,GO:0032933,GO:0032937,GO:0032937,GO:0036316,GO:0036316,GO:0042472,GO:0042474,GO:0045717,GO:0060021,GO:0060363,GO:0140311

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR INSIG2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 INSIG2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 INSIG2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A INSIG2 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 INSIG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA INSIG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF INSIG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 INSIG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 INSIG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 INSIG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 INSIG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS INSIG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A INSIG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 INSIG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 INSIG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 INSIG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 INSIG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000508C13 INSIG2 N/A 15685193 rna interference,inhibition array technology miRSponge
URS0000508C13 INSIG2 15685193 25416803 mrna cleavage,inhibition array technology TarBase
URS0000237AF9 INSIG2 18185580 22012620 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS00000ED600 INSIG2 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00001E0AEA INSIG2 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00004719AB INSIG2 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003FA24D INSIG2 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001CF056 INSIG2 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 INSIG2 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 INSIG2 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F INSIG2 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 INSIG2 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000279B6F INSIG2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 INSIG2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000334286 INSIG2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 INSIG2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF INSIG2 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HSPA8 INSIG2 25348397 N/A physical interaction ComPPI
RPN1 INSIG2 25348397 N/A physical interaction ComPPI
PSMC3 INSIG2 25348397 N/A physical interaction ComPPI
PSMC6 INSIG2 25348397 N/A physical interaction ComPPI
PSMD14 INSIG2 25348397 N/A physical interaction ComPPI
VCP INSIG2 25348397 N/A physical interaction ComPPI
LMNA INSIG2 25348397 N/A physical interaction ComPPI
BIK INSIG2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LAPTM5 INSIG2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 INSIG2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
INSIG2 SREBF2 12242332 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
INSIG2 SCAP 12242332 12482938 14525934 16549805 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
INSIG2 AMFR 25348397 N/A physical interaction ComPPI
INSIG2 UBQLN2 25348397 N/A physical interaction ComPPI
INSIG2 UBQLN1 25348397 N/A physical interaction ComPPI
INSIG2 PSMC5 25348397 N/A physical interaction ComPPI
INSIG2 BAG6 25348397 N/A physical interaction ComPPI
INSIG2 PSMD11 25348397 N/A physical interaction ComPPI
INSIG2 HSPA5 25348397 N/A physical interaction ComPPI
INSIG2 PSMD13 25348397 N/A physical interaction ComPPI
INSIG2 DSP 25348397 N/A physical interaction ComPPI
INSIG2 ENO1 25348397 N/A physical interaction ComPPI
INSIG2 LGALS7 25348397 N/A physical interaction ComPPI
INSIG2 PSMD4 25348397 N/A physical interaction ComPPI
INSIG2 PSMC2 25348397 N/A physical interaction ComPPI
INSIG2 PSMD12 25348397 N/A physical interaction ComPPI
INSIG2 FAF2 25348397 N/A physical interaction ComPPI
INSIG2 HSPA1A 25348397 N/A physical interaction ComPPI
INSIG2 HSPA1B 25348397 N/A physical interaction ComPPI
INSIG2 HSPA6 25348397 N/A physical interaction ComPPI
INSIG2 PSMA7 25348397 N/A physical interaction ComPPI
INSIG2 INSIG1 25348397 N/A physical interaction ComPPI
INSIG2 RNF139 25348397 N/A physical interaction ComPPI
INSIG2 SREBF1 25348397 N/A physical interaction ComPPI
INSIG2 HMGCR 25348397 N/A physical interaction ComPPI
INSIG2 CD40 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
INSIG2 CREB3L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
INSIG2 KIR2DL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
INSIG2 AQP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
INSIG2 CD79A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
INSIG2 PRLR 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
INSIG2 IFNGR2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
INSIG2 EBP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
JUP INSIG2 25348397 N/A physical interaction ComPPI
PSMB1 INSIG2 25348397 N/A physical interaction ComPPI
PSMB3 INSIG2 25348397 N/A physical interaction ComPPI
ADRM1 INSIG2 25348397 N/A physical interaction ComPPI

Visualization










  Return