Gene Information gene info

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GENE：LFNG

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LFNG
FullNmae LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6560
EnsembleID ENSG00000106003
Uniprot Q8NES3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LFNG immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LFNG GO:0000139,GO:0001541,GO:0001756,GO:0002315,GO:0005576,GO:0007386,GO:0008593,GO:0008593,GO:0009887,GO:0014807,GO:0030217,GO:0033829,GO:0033829,GO:0033829,GO:0033829,GO:0045747,GO:0046872,GO:0051446,GO:1902367,GO:1903561

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LFNG hsa:3955 path:hsa00514 Other types of O-glycan biosynthesis - Homo sapiens (human)
LFNG hsa:3955 path:hsa04330 Notch signaling pathway - Homo sapiens (human)
LFNG hsa:3955 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LFNG DLL3 10934472 23331499 stimulation N/A SignaLink,SignaLink
LFNG NOTCH1 10934472 10935626 12486116 18988627 23331499 interaction type N/A SignaLink,SignaLink
LFNG DLL1 11346656 23331499 stimulation N/A SignaLink,SignaLink
LFNG JAG1 15574878 23331499 inhibition N/A SignaLink
POFUT1 LFNG 15380241 23331499 stimulation N/A SignaLink
LFNG NOTCH2 10934472 11346656 23331499 interaction type N/A SignaLink

Source Target Pmid Interactiontype Methods Database
SMARCA4 LFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 LFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 LFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 LFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 LFNG 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000028BB8 LFNG 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00001F0C23 LFNG 23484856 25416803 27292025 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS0000330617 LFNG 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F LFNG 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 LFNG 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 LFNG 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 LFNG 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E628F LFNG 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 LFNG 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 LFNG 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF LFNG 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFBE3 LFNG 25416803 27311960 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
LFNG JAG1 25361965 interaction type N/A PTMCode2
JAG1 LFNG 25361965 interaction type N/A PTMCode2
LFNG NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 LFNG 25361965 interaction type N/A PTMCode2
LFNG DLL1 25361965 interaction type N/A PTMCode2
DLL1 LFNG 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NOTCH1 LFNG 10935626 12486116 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CCT7 LFNG 25348397 N/A physical interaction ComPPI
LFNG NOTCH2 11346656 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LFNG APP 25348397 N/A physical interaction ComPPI
LFNG CCT2 25348397 N/A physical interaction ComPPI
LFNG CCT6A 25348397 N/A physical interaction ComPPI
LFNG DLL1 11346656 27898060 stimulant N/A OmniPath
SIX1 LFNG 14695375 27898060 stimulant N/A OmniPath
LFNG NOTCH1 10934472 10935626 12486116 27898060 inhibition,stimulant N/A OmniPath
LFNG JAG1 15574878 27898060 inhibition N/A OmniPath
LFNG NOTCH2 10934472 11346656 1134666 27898060 inhibition,stimulant N/A OmniPath
POFUT1 LFNG 15380241 27898060 stimulant N/A OmniPath
LFNG DLL3 10934472 27898060 stimulant N/A OmniPath

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