Gene Information gene info

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GENE：MACROD1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MACROD1
FullNmae mono-ADP ribosylhydrolase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29598
EnsembleID ENSG00000133315
Uniprot Q9BQ69

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MACROD1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MACROD1 GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006974,GO:0006974,GO:0016798,GO:0019213,GO:0042278,GO:0042278,GO:0051725,GO:0140291,GO:0140291,GO:0140293,GO:0140293

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR MACROD1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MACROD1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MACROD1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C MACROD1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ESR1 MACROD1 15691879 trascriptional regulation,stimulation inferred by curator TFlink
SP1 MACROD1 15691879 18206366 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MACROD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MACROD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MACROD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MACROD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MACROD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MACROD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MACROD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MACROD1 18971253 19698236 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MACROD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MACROD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RARA MACROD1 19698236 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 MACROD1 18206366 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
KRT18 MACROD1 20035625 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down ComPPI,IntAct
DDX21 MACROD1 25348397 N/A physical interaction ComPPI
BAG3 MACROD1 25348397 N/A physical interaction ComPPI
PPP2R1A MACROD1 25348397 N/A physical interaction ComPPI
KPNA1 MACROD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN6 MACROD1 25348397 N/A physical interaction ComPPI
HBA1 MACROD1 25348397 N/A physical interaction ComPPI
CETN2 MACROD1 25348397 N/A physical interaction ComPPI
DHX9 MACROD1 25348397 N/A physical interaction ComPPI
DLD MACROD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
YBX1 MACROD1 25348397 N/A physical interaction ComPPI
EIF2AK2 MACROD1 25348397 N/A physical interaction ComPPI
PARP1 MACROD1 25348397 N/A physical interaction ComPPI
XRCC5 MACROD1 25348397 N/A physical interaction ComPPI
PARP2 MACROD1 25348397 N/A physical interaction ComPPI
RPA1 MACROD1 25348397 N/A physical interaction ComPPI
IKBKB MACROD1 25348397 N/A physical interaction ComPPI
HNRNPU MACROD1 25348397 N/A physical interaction ComPPI
PTPN7 MACROD1 25348397 N/A physical interaction ComPPI
XRCC6 MACROD1 25348397 N/A physical interaction ComPPI
HNRNPL MACROD1 25348397 N/A physical interaction ComPPI
ERC1 MACROD1 25348397 N/A physical interaction ComPPI
EXOC3 MACROD1 25348397 N/A physical interaction ComPPI
MACROD1 IKBKG 25348397 N/A physical interaction ComPPI
MACROD1 CSTF3 25348397 N/A physical interaction ComPPI
MACROD1 PTP4A1 25348397 N/A physical interaction ComPPI
MACROD1 H2AX 25348397 N/A physical interaction ComPPI
MACROD1 SUPT16H 25348397 N/A physical interaction ComPPI
MACROD1 XPC 25348397 N/A physical interaction ComPPI
MACROD1 SSRP1 25348397 N/A physical interaction ComPPI
MACROD1 LIG3 25348397 N/A physical interaction ComPPI
MACROD1 HBE1 25348397 N/A physical interaction ComPPI
MACROD1 ESR1 17914104 20035625 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,two hybrid,pull down ComPPI,IntAct,OmniPath
MACROD1 VCAM1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
MACROD1 RELA 21483817 24234451 colocalization,association,physical association anti bait coimmunoprecipitation,pull down,confocal microscopy IntAct
MACROD1 UXT 21483817 24234451 association pull down IntAct
MACROD1 NFKBIA 21483817 24234451 physical association chromatin immunoprecipitation assay IntAct
MACROD1 FZD1 12857724 27898060 stimulant N/A OmniPath

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