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GENE：NECTIN3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NECTIN3
FullNmae nectin cell adhesion molecule 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17664
EnsembleID ENSG00000177707
Uniprot Q9NQS3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NECTIN3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NECTIN3 GO:0002089,GO:0005515,GO:0005886,GO:0005886,GO:0005911,GO:0005912,GO:0007156,GO:0007156,GO:0007157,GO:0009566,GO:0030424,GO:0030425,GO:0042803,GO:0043296,GO:0044291,GO:0046718,GO:0050839,GO:0060042,GO:0061951,GO:0098686,GO:0098839,GO:1902414

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NECTIN3 hsa:25945 path:hsa04514 Cell adhesion molecules - Homo sapiens (human)
NECTIN3 hsa:25945 path:hsa04520 Adherens junction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NECTIN3 TIGIT 22285893 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
E2F4 NECTIN3 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NECTIN3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 NECTIN3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NECTIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NECTIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NECTIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NECTIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NECTIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 NECTIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 NECTIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 NECTIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 NECTIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003A5E54 NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001A405B NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D NECTIN3 22100165 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KRTAP10-8 NECTIN3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BAG3 NECTIN3 25348397 N/A physical interaction ComPPI
KRTAP10-7 NECTIN3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NECTIN2 NECTIN3 12011057 14525934 21982860 23758976 24234451 25348397 physical association experimental interaction detection,protein array,surface plasmon resonance,physical interaction,in vitro,surface plasmon resonance array ComPPI,HPRD,IntAct
KRTAP4-2 NECTIN3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FBXO2 NECTIN3 25348397 N/A physical interaction ComPPI
PVR NECTIN3 25348397 N/A physical interaction,physical interaction,in vitro,surface plasmon resonance array ComPPI
NECTIN1 NECTIN3 12011057 14525934 21982860 24234451 25348397 physical association cosedimentation in solution,experimental interaction detection,fluorescence-activated cell sorting,protein array,physical interaction,in vitro,surface plasmon resonance array ComPPI,HPRD,IntAct
NECTIN3 PKHD1 25348397 N/A in vitro,in vivo ComPPI
NECTIN3 PARD3 12515806 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NECTIN3 AFDN 11024295 15811349 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
NECTIN3 TIGIT 21982860 24234451 25348397 physical association protein array,physical interaction ComPPI,IntAct
NECTIN3 RGS20 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NECTIN3 KRTAP10-9 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NECTIN3 KRTAP10-3 25348397 N/A physical interaction ComPPI
NECTIN3 NOTCH2NLA 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NECTIN3 LGALS8 25348397 N/A physical interaction ComPPI
NECTIN3 NPTX1 25348397 N/A physical interaction ComPPI
NECTIN3 SDF2 25348397 N/A physical interaction ComPPI
NECTIN3 ASPH 25348397 N/A physical interaction ComPPI
NECTIN3 COL14A1 25348397 N/A physical interaction ComPPI
NECTIN3 MAK 25348397 N/A physical interaction ComPPI
NECTIN3 ERO1B 25348397 N/A physical interaction ComPPI
NECTIN3 INPP5K 25348397 N/A physical interaction ComPPI
NECTIN3 PDK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NECTIN3 FBXO7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NECTIN3 PPP4R3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NECTIN3 NLRP3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NECTIN3 CHMP4B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NECTIN3 SDF2L1 25348397 N/A physical interaction ComPPI
NECTIN3 DBN1 23750010 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
NECTIN3 SDCBP 24234451 25348397 26787460 N/A phage display ComPPI,IntAct
AFDN NECTIN3 10744716 11024295 15811349 27898060 N/A N/A OmniPath
PVR NECTIN3 12759359 22902367 27898060 N/A N/A OmniPath

Visualization










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