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GENE：SEMA7A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SEMA7A
FullNmae semaphorin 7A (JohnMiltonHagen blood group)
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10741
EnsembleID ENSG00000138623
Uniprot O75326

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SEMA7A pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SEMA7A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SEMA7A GO:0001649,GO:0001755,GO:0001934,GO:0005178,GO:0005515,GO:0005886,GO:0006954,GO:0006955,GO:0007229,GO:0007229,GO:0007411,GO:0009897,GO:0009897,GO:0016020,GO:0021988,GO:0030215,GO:0030335,GO:0045499,GO:0045773,GO:0045773,GO:0048675,GO:0048843,GO:0050727,GO:0050727,GO:0050919,GO:0060907,GO:0060907,GO:0062023,GO:0070374,GO:0070374,GO:0071526

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SEMA7A hsa:8482 path:hsa04360 Axon guidance - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SEMA7A PLXNC1 20727575 23180781 physical association isothermal titration calorimetry InnateDB

Source Target Pmid Interactiontype Methods Database
AR SEMA7A 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SEMA7A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 SEMA7A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SEMA7A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 SEMA7A 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SEMA7A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SEMA7A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SEMA7A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SEMA7A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SEMA7A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SEMA7A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SEMA7A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SEMA7A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SEMA7A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SEMA7A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SEMA7A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SEMA7A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 SEMA7A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001B341F SEMA7A 24725595 25416803 mrna cleavage,inhibition western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000009A9A2 SEMA7A 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001D69F6 SEMA7A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 SEMA7A 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003883FE SEMA7A 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003B6B84 SEMA7A 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000025EABA SEMA7A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B SEMA7A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000004CA3 SEMA7A 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003CF1AD SEMA7A 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000018E72A SEMA7A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 SEMA7A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 SEMA7A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 SEMA7A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F SEMA7A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 SEMA7A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA SEMA7A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 SEMA7A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001270D3 SEMA7A 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000CBE63 SEMA7A 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000292B1 SEMA7A 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA SEMA7A 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 SEMA7A 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C SEMA7A 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00000EBD4B SEMA7A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 SEMA7A 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NFATC1 SEMA7A 25348397 N/A physical interaction ComPPI
NCK1 SEMA7A 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
GRB2 SEMA7A 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SLC9A1 SEMA7A 25348397 N/A physical interaction ComPPI
CKAP4 SEMA7A 25348397 N/A physical interaction ComPPI
FYN SEMA7A 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SLC12A9 SEMA7A 25348397 N/A physical interaction ComPPI
SEMA7A PLXNC1 10520995 14525934 20727575 24234451 25348397 physical association experimental interaction detection,isothermal titration calorimetry,x-ray crystallography,in vitro,in vivo ComPPI,HPRD,IntAct
SEMA7A SOAT1 25348397 N/A physical interaction ComPPI
SEMA7A DPY19L1 25348397 N/A physical interaction ComPPI
SEMA7A UNC93B1 25348397 N/A physical interaction ComPPI
SEMA7A TAPT1 25348397 N/A physical interaction ComPPI
SEMA7A TMEM214 25348397 N/A physical interaction ComPPI
SEMA7A TMEM39B 25348397 N/A physical interaction ComPPI
SEMA7A ATP11C 25348397 N/A physical interaction ComPPI
SEMA7A LMF2 25348397 N/A physical interaction ComPPI
SEMA7A SGPL1 25348397 N/A physical interaction ComPPI
SEMA7A CLCC1 25348397 N/A physical interaction ComPPI
SEMA7A ABL1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SEMA7A PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
SEMA7A SEMA7A 14525934 17377534 20727575 24234451 N/A experimental interaction detection,molecular sieving HPRD,IntAct
SEMA7A ITGB1 27898060 7377534 stimulant N/A OmniPath
SEMA7A PLXNC1 10520995 20727575 27898060 stimulant N/A OmniPath
SEMA7A ITGA1 27898060 7377534 N/A N/A OmniPath

Visualization










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