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GENE：CBR4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CBR4
FullNmae carbonyl reductase 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25891
EnsembleID ENSG00000145439
Uniprot Q8N4T8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CBR4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CBR4 GO:0003955,GO:0004316,GO:0004316,GO:0005515,GO:0005759,GO:0005759,GO:0006633,GO:0006633,GO:0006633,GO:0008753,GO:0016616,GO:0044597,GO:0044598,GO:0048038,GO:0048038,GO:0051289,GO:0051290,GO:0070402,GO:1990204,GO:1990204

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CBR4 hsa:84869 path:hsa00061 Fatty acid biosynthesis - Homo sapiens (human)
CBR4 hsa:84869 path:hsa01100 Metabolic pathways - Homo sapiens (human)
CBR4 hsa:84869 path:hsa01212 Fatty acid metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR CBR4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CBR4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CBR4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CBR4 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CBR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CBR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CBR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CBR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CBR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CBR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CBR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CBR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CBR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CBR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 CBR4 20584899 rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 CBR4 18668040 20584899 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000A07C1 CBR4 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase

Source Target Pmid Interactiontype Methods Database
NF2 CBR4 25348397 N/A physical interaction ComPPI
TRIM25 CBR4 25348397 N/A physical interaction ComPPI
ELAVL1 CBR4 25348397 N/A physical interaction ComPPI
CLPP CBR4 24234451 25348397 26058080 association proximity-dependent biotin identification ComPPI,IntAct
ZXDC CBR4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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