Gene Information gene info

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GENE：AATK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AATK
FullNmae apoptosis associated tyrosine kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21
EnsembleID ENSG00000181409
Uniprot Q6ZMQ8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AATK immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AATK GO:0004674,GO:0004713,GO:0005515,GO:0005524,GO:0005575,GO:0007420,GO:0008150,GO:0016020,GO:0016310,GO:0038083,GO:0048471,GO:0106310

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AATK STK39 14563843 17267545 23331499 inhibition N/A SignaLink
AATK CDK5R1 14521924 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
CTCF AATK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AATK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS AATK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A AATK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 AATK 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 AATK 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
CDK5 AATK 25361965 interaction type N/A PTMCode2
AATK CDK5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPP1CC AATK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DPM1 AATK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP1CB AATK 25348397 N/A physical interaction ComPPI
PTPN6 AATK 25348397 N/A physical interaction ComPPI
CDK5R1 AATK 14521924 24234451 25348397 phosphorylation reaction two hybrid,protein kinase assay ComPPI,IntAct
PTPN18 AATK 25348397 N/A physical interaction ComPPI
PTPN11 AATK 25348397 N/A physical interaction ComPPI
MTMR10 AATK 25348397 N/A physical interaction ComPPI
PPM1A AATK 25348397 N/A physical interaction ComPPI
PPP1CA AATK 22321011 24234451 25348397 25852190 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
DNAJA3 AATK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPN7 AATK 25348397 N/A physical interaction ComPPI
DUSP1 AATK 25348397 N/A physical interaction ComPPI
PTPRR AATK 25348397 N/A physical interaction ComPPI
DUSP5 AATK 25348397 N/A physical interaction ComPPI
PTPN12 AATK 25348397 N/A physical interaction ComPPI
DUSP14 AATK 25348397 N/A physical interaction ComPPI
HSPB1 AATK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTEN AATK 25348397 N/A physical interaction ComPPI
CDC14A AATK 25348397 N/A physical interaction ComPPI
CDK5 AATK 25348397 N/A anti bait coimmunoprecipitation ComPPI
SSR4 AATK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SBF1 AATK 25348397 N/A physical interaction ComPPI
PPM1B AATK 25348397 N/A physical interaction ComPPI
STK39 AATK 25348397 N/A physical interaction ComPPI
CDC25B AATK 25348397 N/A physical interaction ComPPI
DUSP6 AATK 25348397 N/A physical interaction ComPPI
PPP3CA AATK 25348397 N/A physical interaction ComPPI
PPP3CB AATK 25348397 N/A physical interaction ComPPI
ILKAP AATK 25348397 N/A physical interaction ComPPI
DNAJA1 AATK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPM1F AATK 25348397 N/A physical interaction ComPPI
RCN1 AATK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EYA2 AATK 25348397 N/A physical interaction ComPPI
STYX AATK 25348397 N/A physical interaction ComPPI
MTMR6 AATK 25348397 N/A physical interaction ComPPI
MTMR9 AATK 25348397 N/A physical interaction ComPPI
MTMR8 AATK 25348397 N/A physical interaction ComPPI
SLC25A11 AATK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ASB12 AATK 25348397 N/A physical interaction ComPPI
ATAD3A AATK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A12 AATK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A22 AATK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A1 AATK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAB1 AATK 25348397 N/A physical interaction ComPPI
ACTC1 AATK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AATK P4HA1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AATK SLC25A13 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AATK PPM1K 25348397 N/A physical interaction ComPPI
AATK PPM1M 25348397 N/A physical interaction ComPPI
AATK PTPN20 25348397 N/A physical interaction ComPPI
AATK DUSP9 25348397 N/A physical interaction ComPPI
AATK DUSP29 25348397 N/A physical interaction ComPPI
AATK PTPDC1 25348397 N/A physical interaction ComPPI
AATK TPTE2 25348397 N/A physical interaction ComPPI
AATK EYA4 25348397 N/A physical interaction ComPPI
BDKRB2 AATK 24234451 28298427 physical association ubiquitin reconstruction IntAct
AATK CDK5R1 14521924 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009C3114 AATK 27087310 direct interaction,inhibition N/A NPInter

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