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GENE：MRPS22

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRPS22
FullNmae mitochondrial ribosomal protein S22
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14508
EnsembleID ENSG00000175110
Uniprot P82650

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRPS22 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MRPS22 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MRPS22 GO:0003735,GO:0003735,GO:0005739,GO:0005743,GO:0005743,GO:0005761,GO:0005763,GO:0005763,GO:0005763,GO:0008150,GO:0032543

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MRPS22 NFKBIL1 17353931 23180781 physical association anti tag coimmunoprecipitation,affinity technology InnateDB
RNF2 MRPS22 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 MRPS22 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 MRPS22 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MRPS22 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 MRPS22 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MRPS22 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
NPM1 MRPS22 25348397 N/A physical interaction ComPPI
FASTKD3 MRPS22 20869947 24234451 25348397 association tandem affinity purification ComPPI,IntAct
UBL4A MRPS22 25348397 N/A physical interaction ComPPI
ZNF707 MRPS22 25348397 N/A physical interaction ComPPI
SMURF2 MRPS22 25348397 N/A physical interaction ComPPI
BTK MRPS22 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SNRNP70 MRPS22 25348397 N/A physical interaction ComPPI
JUN MRPS22 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 MRPS22 25348397 N/A physical interaction ComPPI
CUL3 MRPS22 25348397 N/A physical interaction ComPPI
DAP3 MRPS22 25348397 N/A physical interaction ComPPI
UBC MRPS22 25348397 N/A physical interaction ComPPI
DLD MRPS22 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 MRPS22 25348397 N/A physical interaction ComPPI
BTRC MRPS22 25348397 N/A physical interaction ComPPI
YBX1 MRPS22 22118625 24234451 25348397 association tandem affinity purification ComPPI,IntAct
E4F1 MRPS22 25348397 N/A physical interaction ComPPI
MYC MRPS22 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
C1QBP MRPS22 25348397 N/A physical interaction ComPPI
QARS1 MRPS22 25348397 N/A physical interaction ComPPI
RPS6 MRPS22 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
CUL1 MRPS22 25348397 N/A physical interaction ComPPI
SOX2 MRPS22 25348397 N/A physical interaction ComPPI
RNF2 MRPS22 25348397 N/A physical interaction ComPPI
SHD MRPS22 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MAP1LC3A MRPS22 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
AURKA MRPS22 25348397 N/A physical interaction ComPPI
PRKN MRPS22 25348397 N/A physical interaction ComPPI
H3C1 MRPS22 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
CAND1 MRPS22 25348397 N/A physical interaction ComPPI
PDK1 MRPS22 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BARD1 MRPS22 25348397 N/A physical interaction ComPPI
SMURF1 MRPS22 25348397 N/A physical interaction ComPPI
ESR1 MRPS22 21182203 24234451 25348397 association pull down ComPPI,IntAct
ESR2 MRPS22 21182203 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient,physical interaction ComPPI,IntAct
RPS6KB2 MRPS22 25348397 N/A physical interaction ComPPI
RPL6 MRPS22 25348397 N/A physical interaction ComPPI
AURKAIP1 MRPS22 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRA2A MRPS22 25348397 N/A physical interaction ComPPI
FBXW11 MRPS22 25348397 N/A physical interaction ComPPI
CEP250 MRPS22 25348397 N/A physical interaction ComPPI
LUC7L MRPS22 25348397 N/A physical interaction ComPPI
TARDBP MRPS22 25348397 N/A physical interaction ComPPI
AGO2 MRPS22 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
AGO1 MRPS22 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SHMT2 MRPS22 25348397 N/A physical interaction ComPPI
HSPD1 MRPS22 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPS34 MRPS22 25348397 N/A physical interaction ComPPI
HDGF MRPS22 25348397 N/A physical interaction ComPPI
HNRNPA1 MRPS22 25348397 N/A physical interaction ComPPI
PTCD3 MRPS22 25348397 N/A physical interaction ComPPI
FBL MRPS22 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
POU5F1 MRPS22 25348397 N/A physical interaction ComPPI
AIFM1 MRPS22 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SUMO4 MRPS22 14525934 16236267 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MRPS22 NFKBIL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS22 MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS22 MRPS18B 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
MRPS22 MRPS25 25348397 N/A physical interaction ComPPI
MRPS22 MRPS35 25348397 N/A physical interaction ComPPI
MRPS22 MRPS26 25348397 N/A physical interaction ComPPI
MRPS22 TMEM126A 25348397 N/A physical interaction ComPPI
MRPS22 GRSF1 25348397 N/A physical interaction ComPPI
MRPS22 HAUS2 25348397 N/A physical interaction ComPPI
MRPS22 TP53 22653443 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS22 ZC3H3 25348397 N/A physical interaction ComPPI
MRPS22 RPS8 25348397 N/A physical interaction ComPPI
MRPS22 TRMT10B 25348397 N/A physical interaction ComPPI
MRPS22 MRPS31 25348397 N/A physical interaction ComPPI
MRPS22 MRPS5 25348397 N/A physical interaction ComPPI
MRPS22 MRPS11 25348397 N/A physical interaction ComPPI
MRPS22 MRPS2 25348397 N/A physical interaction ComPPI
MRPS22 MRPS27 25348397 N/A physical interaction ComPPI
MRPS22 MRPS28 25348397 N/A physical interaction ComPPI
MRPS22 MRPS9 25348397 N/A physical interaction ComPPI
MRPS22 GBA2 25348397 N/A physical interaction ComPPI
MRPS22 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MRPS22 NOP53 25348397 N/A physical interaction ComPPI
MRPS22 MRPS15 25348397 N/A physical interaction ComPPI
MRPS22 SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct
MRPS22 SCO1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MGST3 MRPS22 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRMT61B MRPS22 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPS23 MRPS22 25348397 N/A physical interaction ComPPI
PSME3IP1 MRPS22 25348397 N/A physical interaction ComPPI
MKI67 MRPS22 24234451 26949251 association anti tag coimmunoprecipitation IntAct
MRPS22 FGGY 24234451 30021884 physical association cross-linking study IntAct
L1TD1 MRPS22 24234451 25702638 association anti bait coimmunoprecipitation IntAct

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