Gene Information gene info

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GENE：DPH1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DPH1
FullNmae diphthamide biosynthesis 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3003
EnsembleID ENSG00000108963
Uniprot Q9BZG8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DPH1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DPH1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
DPH1 GO:0005515,GO:0005654,GO:0005829,GO:0017183,GO:0017183,GO:0030054,GO:0032991,GO:0046872,GO:0051539,GO:0090560

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 DPH1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DPH1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 DPH1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF DPH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 DPH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DPH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DPH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DPH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F4AC3 DPH1 16822819 25416803 mrna cleavage,inhibition array technology TarBase
URS00000600E6 DPH1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 DPH1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
DPH1 TP53 25361965 interaction type N/A PTMCode2
TP53 DPH1 25361965 interaction type N/A PTMCode2
DPH1 EEF2 25361965 interaction type N/A PTMCode2
EEF2 DPH1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HSPA8 DPH1 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
ZNRD2 DPH1 25348397 N/A physical interaction ComPPI
RBM8A DPH1 11013075 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
UBC DPH1 25348397 N/A physical interaction ComPPI
HSPA5 DPH1 11013075 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
TNFRSF1A DPH1 25348397 N/A physical interaction ComPPI
TP73 DPH1 25348397 N/A physical interaction ComPPI
EFNB2 DPH1 25348397 N/A physical interaction ComPPI
CAMK2D DPH1 25348397 N/A physical interaction ComPPI
TFCP2 DPH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MMS19 DPH1 25348397 N/A physical interaction ComPPI
TP63 DPH1 25348397 N/A physical interaction ComPPI
PRPF4 DPH1 25348397 N/A physical interaction ComPPI
EEF2 DPH1 25348397 N/A physical interaction ComPPI
CARD8 DPH1 25348397 N/A physical interaction ComPPI
FAS DPH1 25348397 N/A physical interaction ComPPI
DPH1 TP53 25348397 N/A physical interaction ComPPI
DPH1 MOV10 25348397 N/A physical interaction ComPPI
DPH1 NXF1 25348397 N/A physical interaction ComPPI
DPH1 SPINT2 25348397 N/A physical interaction ComPPI
DPH1 SULT4A1 25348397 N/A physical interaction ComPPI
DPH1 PLSCR4 25348397 N/A physical interaction ComPPI
DPH1 KPTN 25348397 N/A physical interaction ComPPI
DPH1 GFOD1 25348397 N/A physical interaction ComPPI
DPH1 WIPI2 25348397 N/A physical interaction ComPPI
DPH1 DPH2 23645155 24422557 25348397 27898060 N/A physical interaction ComPPI,OmniPath
DPH1 IMPDH1 25348397 N/A physical interaction ComPPI
DPH1 P2RX5 25348397 N/A physical interaction ComPPI
DPH1 ARSG 25348397 N/A physical interaction ComPPI
DPH1 RGS20 25348397 N/A physical interaction ComPPI
DPH1 MYCL 25348397 N/A physical interaction ComPPI
DPH1 RAB30 25348397 N/A physical interaction ComPPI
DPH1 TULP3 25348397 N/A physical interaction ComPPI

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