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GENE：EPC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EPC1
FullNmae enhancer of polycomb homolog 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19876
EnsembleID ENSG00000120616
Uniprot Q9H2F5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EPC1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EPC1 GO:0000122,GO:0000724,GO:0000786,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005730,GO:0005737,GO:0006351,GO:0006357,GO:0007286,GO:0016604,GO:0031965,GO:0032777,GO:0032777,GO:0035092,GO:0035267,GO:0035861,GO:0042981,GO:0045814,GO:0045892,GO:0045893,GO:0045893,GO:0045944,GO:0045944,GO:0051726,GO:0140463,GO:0140767,GO:1905168,GO:2000779

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EPC1 hsa:80314 path:hsa03082 ATP-dependent chromatin remodeling - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EPC1 BRD8 17320397 19164757 26192618 interaction type N/A ACSN
EPC1 DMAP1 14966270 17320397 19164757 23180781 26192618 interaction type,physical association tandem affinity purification ACSN,InnateDB
EPC1 ING3 17320397 19164757 26192618 interaction type N/A ACSN
EPC1 MRGBP 17320397 19164757 26192618 interaction type N/A ACSN
HOPX EPC1 17192267 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
KAT5 EPC1 14966270 23180781 physical association tandem affinity purification InnateDB
ING3 EPC1 14966270 23180781 physical association anti tag coimmunoprecipitation InnateDB
E2F6 EPC1 15536069 23180781 physical association anti tag coimmunoprecipitation InnateDB
EPC1 TRIM27 10976108 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 EPC1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 EPC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 EPC1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 EPC1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 EPC1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 EPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 EPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 EPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR EPC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB EPC1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00004B4B85 EPC1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C48FA EPC1 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MORF4L2 EPC1 25348397 N/A physical interaction ComPPI
E2F6 EPC1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
MRGBP EPC1 15647280 16230350 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTB EPC1 25348397 N/A physical interaction ComPPI
RINT1 EPC1 24234451 25348397 25416956 physical association physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FOXR2 EPC1 25348397 N/A physical interaction ComPPI
EZH2 EPC1 25348397 N/A physical interaction ComPPI
SRF EPC1 19359245 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RUVBL1 EPC1 16230350 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MYC EPC1 21150319 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PPP2CA EPC1 25348397 N/A physical interaction ComPPI
MORF4L1 EPC1 25348397 N/A physical interaction ComPPI
BRD8 EPC1 25348397 N/A physical interaction ComPPI
MED23 EPC1 25348397 N/A physical interaction ComPPI
TRRAP EPC1 25348397 N/A physical interaction ComPPI
ACTL6A EPC1 15647280 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
EED EPC1 25348397 N/A physical interaction ComPPI
HOPX EPC1 17192267 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TRIM27 EPC1 10976108 11779184 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
DMAP1 EPC1 25348397 N/A physical interaction ComPPI
YEATS4 EPC1 25348397 N/A physical interaction ComPPI
EPC1 ING3 25348397 N/A physical interaction ComPPI
EPC1 KAT5 25348397 N/A physical interaction ComPPI
EPC1 H2AZ1 25348397 N/A physical interaction ComPPI
EPC1 KRT15 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EPC1 PLAC1 25348397 N/A physical interaction ComPPI
EPC1 FOXR1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
EPC1 H2BC1 25348397 N/A physical interaction ComPPI
EPC1 EP400 25348397 N/A physical interaction ComPPI
EPC1 MBTD1 25348397 N/A physical interaction ComPPI
EPC1 RUVBL2 16230350 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EPC1 VPS72 15647280 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EPC1 MEAF6 25348397 N/A physical interaction ComPPI
EPC1 MYCL 25348397 N/A physical interaction ComPPI
EPC1 MAX 25348397 N/A physical interaction ComPPI
EPC1 FOXO6 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
CHRM5 EPC1 24234451 28298427 physical association ubiquitin reconstruction IntAct

Visualization










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