Gene Information gene info

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GENE：CCNT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CCNT1
FullNmae cyclin T1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1599
EnsembleID ENSG00000129315
Uniprot O60563

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CCNT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CCNT1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CCNT1 GO:0000079,GO:0000976,GO:0003677,GO:0003682,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006357,GO:0006366,GO:0007049,GO:0008024,GO:0008024,GO:0008024,GO:0009410,GO:0019901,GO:0032786,GO:0032968,GO:0043923,GO:0043923,GO:0045944,GO:0051301,GO:0061575,GO:0061575,GO:0070063,GO:0070691,GO:0097322,GO:0140297,GO:0140693

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CCNT1 hsa:904 path:hsa03250 Viral life cycle - HIV-1 - Homo sapiens (human)
CCNT1 hsa:904 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CCNT1 CDK9 22012619 22988298 23180781 physical association anti tag coimmunoprecipitation InnateDB
CCNT1 PARP12 23180781 24623795 physical association anti tag coimmunoprecipitation InnateDB
CCNT1 EPSTI1 23180781 24623795 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 CCNT1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 CCNT1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CCNT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CCNT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CCNT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CCNT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CCNT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A CCNT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CCNT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CCNT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PML CCNT1 12727882 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000330617 CCNT1 22205749 rna interference,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000330617 CCNT1 22205749 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000277201 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002AA55A CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000049704B CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 CCNT1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002AB575 CCNT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003E6EFA CCNT1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000009265 CCNT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000058863C CCNT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005DEC41 CCNT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000BF7F9 CCNT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D CCNT1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000017EE98 CCNT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 CCNT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000555DA6 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000001EB3 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDCD1 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000331800 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0920 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001B12A4 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003B6B84 CCNT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 CCNT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005ACA7C CCNT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000237AF9 CCNT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003B59DF CCNT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000078918 CCNT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 CCNT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000047A67D CCNT1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PLK1 CCNT1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
GNAI3 CCNT1 25348397 N/A physical interaction ComPPI
SNW1 CCNT1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC73 CCNT1 24234451 25348397 26659056 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HEXIM2 CCNT1 14525934 15994294 25348397 27898060 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD,OmniPath
CDK6 CCNT1 25348397 N/A physical interaction ComPPI
TP53BP1 CCNT1 25348397 N/A physical interaction ComPPI
SMAD1 CCNT1 19914168 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
DAB2 CCNT1 25348397 N/A physical interaction ComPPI
TAF1 CCNT1 25348397 N/A physical interaction ComPPI
EP300 CCNT1 19387490 24234451 25348397 27898060 acetylation reaction enzymatic study ComPPI,IntAct,OmniPath
SMAD3 CCNT1 19914168 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
KAT2B CCNT1 25348397 N/A physical interaction ComPPI
GRN CCNT1 12588988 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
NTRK1 CCNT1 25348397 N/A physical interaction ComPPI
MYC CCNT1 12944920 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MAPK6 CCNT1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
TP73 CCNT1 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
CTR9 CCNT1 24234451 25348397 26496610 26659056 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AFF1 CCNT1 20153263 24234451 25348397 association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AHR CCNT1 12917420 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
NCOA2 CCNT1 11704662 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
HTATSF1 CCNT1 25348397 N/A physical interaction ComPPI
SOX2 CCNT1 25348397 N/A physical interaction ComPPI
SKP2 CCNT1 11689688 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CIITA CCNT1 25348397 N/A physical interaction ComPPI
PURA CCNT1 11730934 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
TCEA1 CCNT1 20562857 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
GTF2F1 CCNT1 25348397 N/A physical interaction ComPPI
POLR2A CCNT1 25348397 N/A physical interaction ComPPI
CCNT1 GRIPAP1 11704662 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CCNT1 HIC2 12944466 14525934 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
CCNT1 AFF4 12065898 14525934 20153263 21729782 24234451 25348397 association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CCNT1 HEXIM1 12832472 14525934 14580347 15169877 15201869 15940264 16109377 17724342 18281698 18483487 19387490 24234451 24367103 25348397 26186194 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,classical fluorescence spectroscopy,two hybrid,experimental interaction detection,nuclear magnetic resonance,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
CCNT1 CDK9 10465067 10617616 10958691 11145967 11282025 11689688 11713532 11713533 12115727 12894230 14525934 14627702 15528190 18483487 18566585 19387490 19914168 20153263 20535204 20562857 21533037 21729782 22959624 23455922 23602568 24234451 25348397 26659056 9491887 9499409 9872325 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,pull down,x-ray crystallography,physical interaction,ion exchange chromatography,protein kinase assay,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CCNT1 PML 12727882 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
CCNT1 NUFIP1 14525934 15107825 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CCNT1 ESR1 14525934 15940264 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CCNT1 BRD4 14525934 16109376 24234451 24360279 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
CCNT1 HTN1 12832472 14525934 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
CCNT1 MDFIC 25348397 N/A physical interaction ComPPI
CCNT1 SUPT5H 25348397 N/A physical interaction ComPPI
CCNT1 PGC 25348397 N/A physical interaction ComPPI
CCNT1 MEPCE 25348397 N/A physical interaction ComPPI
CCNT1 HNRNPA1 25348397 N/A physical interaction ComPPI
CCNT1 PMS1 25348397 N/A physical interaction ComPPI
CCNT1 MAX 25348397 N/A physical interaction ComPPI
CCNT1 MLLT3 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNT1 KDM1B 25348397 N/A physical interaction ComPPI
CCNT1 NSD3 25348397 N/A physical interaction ComPPI
CCNT1 MLLT1 20153263 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNT1 KMT2A 25348397 N/A physical interaction ComPPI
CCNT1 TERF1 25348397 N/A physical interaction ComPPI
CCNT1 TERF2 25348397 N/A physical interaction ComPPI
CCNT1 TAF7 18391197 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNT1 UBE2A 25348397 N/A physical interaction ComPPI
CCNT1 TUBB4B 25348397 N/A physical interaction ComPPI
CCNT1 RPS9 25348397 N/A physical interaction ComPPI
CCNT1 SMAP 25348397 N/A physical interaction ComPPI
CCNT1 BARD1 25348397 N/A physical interaction ComPPI
CCNT1 BRDT 25348397 N/A physical interaction ComPPI
CCNT1 MED26 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNT1 ELL2 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNT1 LARP7 18281698 18483487 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CCNT1 TMEM150A 25348397 N/A physical interaction ComPPI
CCNT1 CACNG2 25348397 N/A physical interaction ComPPI
CCNT1 ELL3 25348397 N/A physical interaction ComPPI
CCNT1 AIRE 25348397 N/A physical interaction ComPPI
CCNT1 PIP4K2A 25348397 N/A physical interaction ComPPI
CCNT1 MACROH2A2 25348397 N/A physical interaction ComPPI
CCNT1 CTSE 25348397 N/A physical interaction ComPPI
CCNT1 TRIM22 25348397 N/A physical interaction ComPPI
CCNT1 CDK8 20098423 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNT1 PAF1 24234451 25348397 26659056 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNT1 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CCNT1 JMJD6 24234451 24360279 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
CCNT1 NUTM1 25348397 N/A anti tag coimmunoprecipitation ComPPI
LEO1 CCNT1 25348397 N/A physical interaction ComPPI
COMTD1 CCNT1 25348397 N/A physical interaction ComPPI
CCNT1 CCNT1 12832472 14525934 N/A experimental interaction detection HPRD
MKI67 CCNT1 24234451 26949251 association anti tag coimmunoprecipitation IntAct
CCNT1 TAT 10082552 10465067 10545121 11080476 11282025 12486002 12753906 12887902 16135803 16601680 16687403 16893449 17690245 19454010 24367103 27898060 9491887 9872325 N/A N/A OmniPath
PLK1 CCNT1 23977272 27898060 N/A N/A OmniPath
MAML1 CCNT1 15546612 27898060 stimulant N/A OmniPath

Visualization










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