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GENE：ALDH3A2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ALDH3A2
FullNmae aldehyde dehydrogenase 3 family member A2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:403
EnsembleID ENSG00000072210
Uniprot P51648

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ALDH3A2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ALDH3A2 GO:0004028,GO:0004029,GO:0004029,GO:0004029,GO:0005515,GO:0005737,GO:0005778,GO:0005789,GO:0005829,GO:0006081,GO:0006081,GO:0006081,GO:0006631,GO:0007417,GO:0007422,GO:0008544,GO:0033306,GO:0042803,GO:0043231,GO:0043878,GO:0046458,GO:0046577,GO:0050061,GO:0052814

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ALDH3A2 hsa:224 path:hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa00053 Ascorbate and aldarate metabolism - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa00071 Fatty acid degradation - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa00310 Lysine degradation - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa00330 Arginine and proline metabolism - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa00340 Histidine metabolism - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa00380 Tryptophan metabolism - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa00410 beta-Alanine metabolism - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa00561 Glycerolipid metabolism - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa00620 Pyruvate metabolism - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa00770 Pantothenate and CoA biosynthesis - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)
ALDH3A2 hsa:224 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ADRB2 ALDH3A2 23180781 23798571 physical association affinity chromatography technology InnateDB

Source Target Pmid Interactiontype Methods Database
AR ALDH3A2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
TP73 ALDH3A2 19558638 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CEBPA ALDH3A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ALDH3A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ALDH3A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ALDH3A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ALDH3A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ALDH3A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ALDH3A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A ALDH3A2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 ALDH3A2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000AA464 ALDH3A2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
HSPA8 ALDH3A2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CEP19 ALDH3A2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IPO13 ALDH3A2 25348397 N/A physical interaction ComPPI
TOMM22 ALDH3A2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
LMNA ALDH3A2 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
GABARAPL2 ALDH3A2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
AIM2 ALDH3A2 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
NDUFAF4 ALDH3A2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX20 ALDH3A2 25348397 N/A physical interaction ComPPI
ATR ALDH3A2 25348397 N/A physical interaction ComPPI
NELFB ALDH3A2 25348397 N/A physical interaction ComPPI
CUL3 ALDH3A2 25348397 N/A physical interaction ComPPI
KPNB1 ALDH3A2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CANX ALDH3A2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BTRC ALDH3A2 25348397 N/A physical interaction ComPPI
CEP135 ALDH3A2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EVC2 ALDH3A2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TSC2 ALDH3A2 25348397 N/A physical interaction ComPPI
FANCD2 ALDH3A2 25348397 N/A physical interaction ComPPI
HUWE1 ALDH3A2 25348397 N/A physical interaction ComPPI
EGFR ALDH3A2 25348397 N/A physical interaction ComPPI
ARFGEF1 ALDH3A2 25348397 N/A physical interaction ComPPI
MMS19 ALDH3A2 25348397 N/A physical interaction ComPPI
GABARAP ALDH3A2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP1LC3A ALDH3A2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MME ALDH3A2 17342744 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC9A6 ALDH3A2 25348397 N/A physical interaction ComPPI
CAND1 ALDH3A2 25348397 N/A physical interaction ComPPI
SMPD1 ALDH3A2 25348397 N/A physical interaction ComPPI
XPO4 ALDH3A2 25348397 N/A physical interaction ComPPI
TOMM20 ALDH3A2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EIF4G3 ALDH3A2 25348397 N/A physical interaction ComPPI
STAG2 ALDH3A2 25348397 N/A physical interaction ComPPI
FAF2 ALDH3A2 25348397 N/A physical interaction ComPPI
NCDN ALDH3A2 25348397 N/A physical interaction ComPPI
HEATR1 ALDH3A2 25348397 N/A physical interaction ComPPI
FBXL12 ALDH3A2 25348397 N/A physical interaction ComPPI
NINL ALDH3A2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PPP6R2 ALDH3A2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HOOK2 ALDH3A2 25348397 N/A physical interaction ComPPI
GABARAPL1 ALDH3A2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
IFT27 ALDH3A2 24234451 25348397 27173435 association anti tag coimmunoprecipitation ComPPI,IntAct
SLC25A3 ALDH3A2 25348397 N/A physical interaction ComPPI
TUBA1C ALDH3A2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLGRKT ALDH3A2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
INTS1 ALDH3A2 25348397 N/A physical interaction ComPPI
SAAL1 ALDH3A2 25348397 N/A physical interaction ComPPI
TMEM216 ALDH3A2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MTRES1 ALDH3A2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
UQCRQ ALDH3A2 25348397 N/A physical interaction ComPPI
PPP4R3B ALDH3A2 25348397 N/A physical interaction ComPPI
CAND2 ALDH3A2 25348397 N/A physical interaction ComPPI
ATP5MG ALDH3A2 25348397 N/A physical interaction ComPPI
MTCH2 ALDH3A2 25348397 N/A physical interaction ComPPI
CIP2A ALDH3A2 25348397 N/A physical interaction ComPPI
LAMP1 ALDH3A2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
GEMIN4 ALDH3A2 25348397 N/A physical interaction ComPPI
CAPZA2 ALDH3A2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COX6B1 ALDH3A2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
PPP6R1 ALDH3A2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP50 ALDH3A2 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ALDH3A2 TBC1D9B 25348397 N/A physical interaction ComPPI
ALDH3A2 TBC1D15 25348397 N/A physical interaction ComPPI
ALDH3A2 INTS12 25348397 N/A physical interaction ComPPI
ALDH3A2 VPS8 25348397 N/A physical interaction ComPPI
ALDH3A2 LTN1 25348397 N/A physical interaction ComPPI
ALDH3A2 NCAPH2 25348397 N/A physical interaction ComPPI
ALDH3A2 INTS3 25348397 N/A physical interaction ComPPI
ALDH3A2 BRAT1 25348397 N/A physical interaction ComPPI
ALDH3A2 THADA 25348397 N/A physical interaction ComPPI
ALDH3A2 TCTN2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ALDH3A2 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ALDH3A2 TMEM237 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ALDH3A2 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ALDH3A2 ATL3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ALDH3A2 C1ORF112 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ALDH3A2 CTDNEP1 25348397 N/A physical interaction ComPPI
ALDH3A2 ALDH3A1 25348397 N/A physical interaction ComPPI
ALDH3A2 COX14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ALDH3A2 MICOS13 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
ATP6V1C1 ALDH3A2 25348397 N/A physical interaction ComPPI
HSCB ALDH3A2 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
ADCK5 ALDH3A2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct

Visualization










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