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GENE：PUM1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PUM1
FullNmae pumilio RNA binding family member 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14957
EnsembleID ENSG00000134644
Uniprot Q14671

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PUM1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PUM1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PUM1 GO:0000932,GO:0003723,GO:0003723,GO:0003730,GO:0003730,GO:0003730,GO:0005515,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0005829,GO:0007283,GO:0008344,GO:0010494,GO:0010608,GO:0010608,GO:0016441,GO:0030424,GO:0035196,GO:0035196,GO:0035198,GO:0043488,GO:0043488,GO:0048863,GO:0051726,GO:0051983,GO:0060964,GO:0061157,GO:0061158,GO:1900246,GO:2000637

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PUM1 hsa:9698 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PUM1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PUM1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PUM1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 PUM1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 PUM1 21245298 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 PUM1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PUM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PUM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PUM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PUM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PUM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PUM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PUM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PUM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PUM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000BE495 PUM1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000016C318 PUM1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000324096 PUM1 18668040 23622248 25416803 mrna cleavage,inhibition experimental interaction detection,clash TarBase
URS00001C3AC1 PUM1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D PUM1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 PUM1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000157026 PUM1 20371350 21572407 23446348 23622248 25416803 26701625 mrna cleavage,inhibition clip,clash TarBase
URS000021202F PUM1 20371350 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001E0AEA PUM1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 PUM1 21572407 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB PUM1 21572407 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA PUM1 21572407 23313552 23446348 25151966 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000122F23 PUM1 20371350 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000049FAE8 PUM1 20371350 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C308D PUM1 20371350 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237AF9 PUM1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000512C88 PUM1 20371350 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000076995 PUM1 20371350 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005C1F22 PUM1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000054A671 PUM1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 PUM1 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDC5L PUM1 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CDKN1A PUM1 25348397 N/A physical interaction ComPPI
CLNS1A PUM1 25348397 N/A physical interaction ComPPI
ATXN1 PUM1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
BMI1 PUM1 25348397 N/A physical interaction ComPPI
KEAP1 PUM1 25348397 N/A physical interaction ComPPI
EIF5 PUM1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FOXG1 PUM1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SMAD1 PUM1 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
DSTN PUM1 25348397 N/A physical interaction ComPPI
YWHAB PUM1 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 PUM1 25348397 N/A physical interaction ComPPI
PUM1 ELAVL1 25348397 N/A physical interaction ComPPI
PUM1 SIRT7 25348397 N/A physical interaction ComPPI
PUM1 CAND1 25348397 N/A physical interaction ComPPI
PUM1 PAICS 25348397 N/A physical interaction ComPPI
PUM1 ANXA5 25348397 N/A physical interaction ComPPI
PUM1 HSPB1 25348397 N/A physical interaction ComPPI
PUM1 ITGA4 25348397 N/A physical interaction ComPPI
PUM1 FBXO6 25348397 N/A physical interaction ComPPI
PUM1 SAV1 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PUM1 AURKB 25348397 N/A physical interaction ComPPI
PUM1 EGFR 25348397 N/A physical interaction ComPPI
PUM1 RBFOX2 25348397 N/A physical interaction ComPPI
PUM1 FBXW11 25348397 N/A physical interaction ComPPI
PUM1 XPO1 25348397 N/A physical interaction ComPPI
PUM1 MATR3 25348397 N/A physical interaction ComPPI
PUM1 SEC16A 25348397 N/A physical interaction ComPPI
PUM1 FOXQ1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PUM1 EYA2 25348397 N/A physical interaction ComPPI
PUM1 ELAVL2 25348397 N/A physical interaction ComPPI
PUM1 TRIM11 25348397 N/A physical interaction ComPPI
PUM1 LITAF 25348397 N/A physical interaction ComPPI
PUM1 TRIM25 25348397 N/A physical interaction ComPPI
PUM1 G3BP1 25348397 N/A physical interaction ComPPI
PUM1 CNOT8 16715093 24234451 25348397 27898060 N/A pull down,physical interaction ComPPI,IntAct,OmniPath
PUM1 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PUM1 VCAM1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
DICER1 PUM1 21858095 24234451 association anti tag coimmunoprecipitation IntAct

Visualization










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