GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
ADAM22 |
FullNmae |
ADAM metallopeptidase domain 22 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:201 |
EnsembleID |
ENSG00000008277 |
Uniprot |
Q9P0K1 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
ADAM22 |
mitotic_cd |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
ADAM22 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
ADAM22 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
ADAM22 |
GO:0004222,GO:0005178,GO:0005515,GO:0005886,GO:0005886,GO:0006508,GO:0007155,GO:0007162,GO:0007417,GO:0016020,GO:0016020,GO:0030424 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
ETS1 |
ADAM22 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
YBX1 |
ADAM22 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
ADAM22 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
ADAM22 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
ADAM22 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F1 |
ADAM22 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F4 |
ADAM22 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
ADAM22 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
ADAM22 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
ADAM22 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
RUNX1 |
ADAM22 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TAL1 |
ADAM22 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS000039607D |
ADAM22 |
22100165
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000031BC7D |
ADAM22 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000020579D |
ADAM22 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000308E4D |
ADAM22 |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001270D3 |
ADAM22 |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000250A40 |
ADAM22 |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
DLG4 |
ADAM22 |
25348397
|
N/A |
physical interaction |
ComPPI |
LYN |
ADAM22 |
25348397
|
N/A |
physical interaction |
ComPPI |
YWHAB |
ADAM22 |
14525934
16868027
18762889
25348397
27898060
|
N/A |
two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid |
ComPPI,HPRD,OmniPath |
YWHAZ |
ADAM22 |
12589811
14525934
24234451
25348397
|
physical association |
two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,lex-a dimerization assay,in vitro,in vivo,two hybrid |
ComPPI,HPRD,IntAct |
EPS8 |
ADAM22 |
21988832
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
CSNK1E |
ADAM22 |
23455922
24234451
25348397
|
association |
physical interaction,tandem affinity purification |
ComPPI,IntAct |
YWHAQ |
ADAM22 |
25348397
|
N/A |
two hybrid |
ComPPI |
YWHAH |
ADAM22 |
25348397
|
N/A |
anti tag coimmunoprecipitation |
ComPPI |
YWHAE |
ADAM22 |
25348397
|
N/A |
anti tag coimmunoprecipitation |
ComPPI |
RAC2 |
ADAM22 |
21988832
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
ADAM22 |
NXF1 |
25348397
|
N/A |
physical interaction |
ComPPI |
ADAM22 |
APP |
25348397
|
N/A |
physical interaction |
ComPPI |
ADAM22 |
HCK |
25348397
|
N/A |
surface plasmon resonance array |
ComPPI |
ADAM22 |
MYB |
20195357
24234451
25348397
|
physical association |
display technology |
ComPPI,IntAct |
ADAM22 |
SCRIB |
24234451
24550280
25348397
30126976
|
physical association |
phage display,p8 filamentous phage display |
ComPPI,IntAct |
ADAM22 |
LGI1 |
14525934
16990550
|
N/A |
experimental interaction detection |
HPRD |
ADAM22 |
DLG1 |
24234451
30126976
|
N/A |
p8 filamentous phage display |
IntAct |
Visualization