Gene Information gene info

GENE:ADAM22

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ADAM22
FullNmae ADAM metallopeptidase domain 22
LocusType gene with protein product
Status Approved
HGNC_id HGNC:201
EnsembleID ENSG00000008277
Uniprot Q9P0K1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ADAM22 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ADAM22 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ADAM22 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ADAM22 GO:0004222,GO:0005178,GO:0005515,GO:0005886,GO:0005886,GO:0006508,GO:0007155,GO:0007162,GO:0007417,GO:0016020,GO:0016020,GO:0030424

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ADAM22 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ADAM22 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ADAM22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ADAM22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ADAM22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ADAM22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ADAM22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ADAM22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ADAM22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ADAM22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 ADAM22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ADAM22 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000039607D ADAM22 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000031BC7D ADAM22 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D ADAM22 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D ADAM22 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001270D3 ADAM22 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000250A40 ADAM22 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DLG4 ADAM22 25348397 N/A physical interaction ComPPI
LYN ADAM22 25348397 N/A physical interaction ComPPI
YWHAB ADAM22 14525934 16868027 18762889 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
YWHAZ ADAM22 12589811 14525934 24234451 25348397 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,lex-a dimerization assay,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
EPS8 ADAM22 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CSNK1E ADAM22 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
YWHAQ ADAM22 25348397 N/A two hybrid ComPPI
YWHAH ADAM22 25348397 N/A anti tag coimmunoprecipitation ComPPI
YWHAE ADAM22 25348397 N/A anti tag coimmunoprecipitation ComPPI
RAC2 ADAM22 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ADAM22 NXF1 25348397 N/A physical interaction ComPPI
ADAM22 APP 25348397 N/A physical interaction ComPPI
ADAM22 HCK 25348397 N/A surface plasmon resonance array ComPPI
ADAM22 MYB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
ADAM22 SCRIB 24234451 24550280 25348397 30126976 physical association phage display,p8 filamentous phage display ComPPI,IntAct
ADAM22 LGI1 14525934 16990550 N/A experimental interaction detection HPRD
ADAM22 DLG1 24234451 30126976 N/A p8 filamentous phage display IntAct

Visualization