Gene Information gene info

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GENE：ASPA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ASPA
FullNmae aspartoacylase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:756
EnsembleID ENSG00000108381
Uniprot P45381

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ASPA immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ASPA GO:0004046,GO:0005515,GO:0005634,GO:0005829,GO:0005829,GO:0005829,GO:0006083,GO:0006533,GO:0016788,GO:0016811,GO:0019807,GO:0022010,GO:0042802,GO:0046872,GO:0048714

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ASPA hsa:443 path:hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human)
ASPA hsa:443 path:hsa00340 Histidine metabolism - Homo sapiens (human)
ASPA hsa:443 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ASPA ACY3 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
FOXA1 ASPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ASPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 ASPA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004DA9DB ASPA 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001A405B ASPA 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000008C563 ASPA 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002F3336 ASPA 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D ASPA 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C85B2 ASPA 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002152A8 ASPA 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AB32B ASPA 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A760 ASPA 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 ASPA 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C0099 ASPA 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001496AE ASPA 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 ASPA 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041FA2C ASPA 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
WASL ASPA 25348397 N/A physical interaction ComPPI
ACY3 ASPA 24234451 25348397 25416956 25910212 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,split luciferase complementation,validated two hybrid ComPPI,IntAct
KEAP1 ASPA 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,split luciferase complementation,validated two hybrid ComPPI,IntAct
ASPA RUFY1 25348397 N/A physical interaction ComPPI
ASPA PGK2 25348397 N/A physical interaction ComPPI
ASPA DUSP29 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ASPA ASPA 14525934 16189514 17194761 24234451 physical association x-ray crystallography,two hybrid pooling approach,two hybrid HPRD,IntAct

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