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GENE：DLG3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DLG3
FullNmae discs large MAGUK scaffold protein 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2902
EnsembleID ENSG00000082458
Uniprot Q92796

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DLG3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DLG3 cuproptosis 36550822 Next, 11 hub CAGs(cuproptosis-associated genes), including COPB2, MRPL39, PGK1, PRDX1, PCMT1, MPZL3, LACTB2, HSPH1, DIP2B, DLG3, and NFKBIA, were applied to construct a novel prognostic risk signature for BR. cuproptosis-associated gene

Go Annotation:

GeneSymbol Go id
DLG3 GO:0001736,GO:0005515,GO:0005615,GO:0005829,GO:0005886,GO:0005912,GO:0005923,GO:0007268,GO:0008285,GO:0009790,GO:0016323,GO:0019900,GO:0019902,GO:0031594,GO:0031625,GO:0032281,GO:0043005,GO:0043113,GO:0045197,GO:0045197,GO:0061098,GO:0097120,GO:0098609,GO:0098839,GO:0098978,GO:0099072

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DLG3 hsa:1741 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)
DLG3 hsa:1741 path:hsa04530 Tight junction - Homo sapiens (human)
DLG3 hsa:1741 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR DLG3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DLG3 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 DLG3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA DLG3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DLG3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DLG3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DLG3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 DLG3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 DLG3 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 DLG3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 DLG3 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PTK2B DLG3 25361965 interaction type N/A PTMCode2
DLG3 PTK2B 25361965 interaction type N/A PTMCode2
APC DLG3 25361965 interaction type N/A PTMCode2
DLG3 APC 25361965 interaction type N/A PTMCode2
DLG3 GRIK2 25361965 interaction type N/A PTMCode2
GRIK2 DLG3 25361965 interaction type N/A PTMCode2
CRIPT DLG3 25361965 interaction type N/A PTMCode2
DLG3 CRIPT 25361965 interaction type N/A PTMCode2
ATP2B4 DLG3 25361965 interaction type N/A PTMCode2
DLG3 ATP2B4 25361965 interaction type N/A PTMCode2
ERBB4 DLG3 25361965 interaction type N/A PTMCode2
DLG3 ERBB4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ZNF232 DLG3 25348397 N/A physical interaction ComPPI
LIN7A DLG3 14525934 25348397 9753324 N/A experimental interaction detection,in vitro ComPPI,HPRD
BAG3 DLG3 25348397 N/A physical interaction ComPPI
ANXA1 DLG3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
H2BC4 DLG3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
KRT31 DLG3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SEMA4C DLG3 11134026 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
DLG4 DLG3 10026200 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
PTK2B DLG3 12576483 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RACGAP1 DLG3 25348397 N/A physical interaction ComPPI
ERBB4 DLG3 10725395 12175853 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
KHDRBS1 DLG3 25348397 N/A physical interaction ComPPI
SCN5A DLG3 14525934 16637659 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
APC DLG3 25348397 27898060 9188857 N/A physical interaction ComPPI,OmniPath
VTN DLG3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DLGAP1 DLG3 25348397 N/A physical interaction ComPPI
KCNA4 DLG3 14525934 16637659 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PPP1CA DLG3 19389623 24234451 25348397 physical association far western blotting,pull down ComPPI,IntAct
RPS6KA4 DLG3 25348397 N/A physical interaction ComPPI
GRIN1 DLG3 10862698 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CNKSR2 DLG3 14525934 16637659 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
EXOC3 DLG3 25348397 N/A physical interaction ComPPI
EXOC4 DLG3 12738960 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
GRIN2B DLG3 11937501 11997254 12738960 14525934 25348397 27898060 8780649 9278515 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
CUL2 DLG3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ZFP91 DLG3 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
DLG1 DLG3 12351654 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MAPK12 DLG3 14525934 16637659 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ADGRL1 DLG3 10958799 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
DLG3 ATP2B4 11274188 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
DLG3 NLGN3 14525934 25348397 9278515 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
DLG3 GUCY1A2 11572861 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
DLG3 CRIPT 11937501 12070168 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
DLG3 GDA 10542258 10595517 14525934 24234451 25348397 colocalization,physical association affinity chromatography technology,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
DLG3 KCNJ12 14525934 15024025 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DLG3 SYNGAP1 14525934 25348397 9581761 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
DLG3 DLGAP4 14525934 25348397 9115257 N/A two hybrid,two hybrid ComPPI,HPRD
DLG3 SCN4A 14525934 16637659 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
DLG3 CACNG2 14525934 16637659 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
DLG3 GLS2 14525934 16637659 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
DLG3 KCNJ2 14525934 16637659 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
DLG3 DLGAP3 14525934 25348397 9115257 N/A two hybrid,two hybrid ComPPI,HPRD
DLG3 GRIN2A 11937501 12070168 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DLG3 ABCA1 14525934 16192269 16192271 24234451 25348397 27898060 physical association experimental interaction detection,peptide array,in vitro ComPPI,HPRD,IntAct,OmniPath
DLG3 LRP2 12713445 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
DLG3 CAMK2A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG3 KRT35 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG3 KRT85 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG3 KRT34 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG3 KRT82 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG3 KLHDC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG3 H2BC11 25348397 N/A physical interaction ComPPI
DLG3 S100A3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG3 KCNJ18 25348397 N/A physical interaction ComPPI
DLG3 EXOC7 25348397 N/A physical interaction ComPPI
DLG3 NLGN2 25348397 N/A physical interaction ComPPI
DLG3 NLGN1 25348397 N/A physical interaction ComPPI
DLG3 GRIK2 12070168 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
DLG3 GRIK5 25348397 N/A physical interaction ComPPI
DLG3 ATP2B2 25348397 N/A physical interaction ComPPI
DLG3 GRIN2C 11937501 14525934 24234451 25348397 30126976 N/A experimental interaction detection,physical interaction,p8 filamentous phage display ComPPI,HPRD,IntAct
DLG3 ELAVL1 25348397 N/A physical interaction ComPPI
DLG3 TEAD4 25348397 N/A physical interaction ComPPI
DLG3 RHBDL1 25348397 N/A physical interaction ComPPI
DLG3 ARFGAP1 25348397 N/A physical interaction ComPPI
DLG3 AP3B1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG3 RB1CC1 25348397 N/A physical interaction ComPPI
DLG3 COBLL1 25348397 N/A physical interaction ComPPI
DLG3 KCTD2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG3 ACAD8 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG3 WDR91 25348397 N/A physical interaction ComPPI
DLG3 MRPL18 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG3 MRPL22 25348397 N/A physical interaction ComPPI
DLG3 SS18L2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG3 MRPS26 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG3 CNPY2 25348397 N/A physical interaction ComPPI
DLG3 KDELR1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DLG3 RPS8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DLG3 PLEKHA2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KIF1B DLG3 14525934 16637659 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
HSCB DLG3 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
DLG3 CALM2 10026200 14525934 N/A experimental interaction detection,two hybrid HPRD
FRMPD4 DLG3 24234451 30126976 N/A p8 filamentous phage display IntAct
NET1 DLG3 24234451 30126976 N/A p8 filamentous phage display IntAct
FAM163B DLG3 24234451 30126976 N/A p8 filamentous phage display IntAct
CYSLTR2 DLG3 24234451 30126976 N/A p8 filamentous phage display IntAct
DLG3 ATP2B4 11274188 27898060 N/A N/A OmniPath
GRIN2A DLG3 11937501 12070168 27898060 9278515 stimulant N/A OmniPath
DLG3 GDA 10542258 10595517 27898060 N/A N/A OmniPath

Visualization










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