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GENE：FBXL3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FBXL3
FullNmae F-box and leucine rich repeat protein 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13599
EnsembleID ENSG00000005812
Uniprot Q9UKT7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FBXL3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FBXL3 GO:0000151,GO:0004842,GO:0004842,GO:0005515,GO:0005634,GO:0005634,GO:0005829,GO:0005829,GO:0005829,GO:0016567,GO:0016567,GO:0016567,GO:0016604,GO:0019005,GO:0019005,GO:0031146,GO:0031146,GO:0031648,GO:0042752,GO:0043153,GO:0043153,GO:0048511

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FBXL3 hsa:26224 path:hsa04710 Circadian rhythm - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 FBXL3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FBXL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FBXL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FBXL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FBXL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FBXL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FBXL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FBXL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000007FBA FBXL3 20371350 25416803 27292025 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS000021D7C8 FBXL3 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000DDD35 FBXL3 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00002233F4 FBXL3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000035CC3E FBXL3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000A057E FBXL3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 FBXL3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D FBXL3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000157F5 FBXL3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB FBXL3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED FBXL3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB FBXL3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 FBXL3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002AA55A FBXL3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 FBXL3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C FBXL3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 FBXL3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000078918 FBXL3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000047A67D FBXL3 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SKP1 FBXL3 25361965 interaction type N/A PTMCode2
FBXL3 SKP1 25361965 interaction type N/A PTMCode2
CUL1 FBXL3 25361965 interaction type N/A PTMCode2
FBXL3 CUL1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SKP1 FBXL3 10531035 14525934 25348397 N/A two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
HSP90AB1 FBXL3 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
PICK1 FBXL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2D2 FBXL3 25348397 N/A physical interaction ComPPI
HSP90AA1 FBXL3 25348397 N/A physical interaction ComPPI
RFX1 FBXL3 25348397 N/A physical interaction ComPPI
BTG2 FBXL3 25348397 N/A physical interaction ComPPI
CUL1 FBXL3 25348397 N/A physical interaction ComPPI
CDC34 FBXL3 25348397 N/A physical interaction ComPPI
CAND1 FBXL3 25348397 N/A physical interaction ComPPI
CRY2 FBXL3 25348397 N/A physical interaction ComPPI
FBXL3 HSP90AA2P 25348397 N/A physical interaction ComPPI
FBXL3 CRY1 25348397 N/A physical interaction ComPPI
FBXL3 RFX2 25348397 N/A physical interaction ComPPI
FBXL3 MSRA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP2R5D FBXL3 25348397 N/A physical interaction ComPPI
BTG1 FBXL3 25348397 N/A physical interaction ComPPI

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